Radioprotective Potential of Plants and Herbs against the Effects of Ionizing Radiation

Journal of Clinical Biochemistry and Nutrition
Ganesh C Jagetia

Abstract

Ionizing radiations produce deleterious effects in the living organisms and the rapid technological advancement has increased human exposure to ionizing radiations enormously. There is a need to protect humans against such effects of ionizing radiation. Attempts to protect against the deleterious effects of ionizing radiations by pharmacological intervention were made as early as 1949 and efforts are continued to search radioprotectors, which may be of great help for human application. This review mainly dwells on the radioprotective potential of plant and herbal extracts. The results obtained from in vitro and in vivo studies indicate that several botanicals such as Gingko biloba, Centella asiatica, Hippophae rhamnoides, Ocimum sanctum, Panax ginseng, Podophyllum hexandrum, Amaranthus paniculatus, Emblica officinalis, Phyllanthus amarus, Piper longum, Tinospora cordifoila, Mentha arvensis, Mentha piperita, Syzygium cumini, Zingiber officinale, Ageratum conyzoides, Aegle marmelos and Aphanamixis polystachya protect against radiation-induced lethality, lipid peroxidation and DNA damage. The fractionation-guided evaluation may help to develop new radioprotectors of desired activities.

References

Jan 1, 1988·Pharmacology & Therapeutics·D Q BrownL M Shaw
May 1, 1969·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·J M Yuhas, J B Storer
Jun 1, 1995·Free Radical Biology & Medicine·I EmeritK Asrian
Sep 1, 1993·Surgical Endoscopy·L E SmithM Marohn
Jan 1, 1997·Journal of Natural Products·G M CraggK M Snader
May 20, 1998·International Journal of Radiation Biology·J R Maisin
Feb 5, 2002·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·C A SalinH C Goel
Apr 2, 2002·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·H C GoelA K Sinha
Apr 11, 2002·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Ganesh Chandra Jagetia, Manjeshwar Shrinath Baliga
May 9, 2002·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·G C JagetiaM Sethukumar Kamath
Jun 18, 2002·Journal of Ethnopharmacology·Namita Samanta, H C Goel
Sep 12, 2002·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·H C GoelAshok Sharma
Nov 30, 2002·Phytotherapy Research : PTR·Jaimala Sharma, Radha Sharma
May 10, 2003·Journal of Ethnopharmacology·Ganesh Chandra JagetiaVikas Jain
May 16, 2003·Phytotherapy Research : PTR·Subhash Pahadiya, Jaimala Sharma
Sep 6, 2003·The Journal of Pharmacy and Pharmacology·Ganesh Chandra JagetiaPrasad M Bhilegaonkar
Nov 8, 2003·The Journal of Pharmacy and Pharmacology·I Prem KumarH C Goel
Dec 17, 2003·Molecular and Cellular Biochemistry·H C GoelN Malhotra
May 11, 2004·Journal of Radiation Research·Harish Chandra GoelRuchi Dogra
May 11, 2004·Journal of Radiation Research·K B Hari Kumar, Ramadasan Kuttan
Jun 19, 2004·International Journal of Radiation Biology·G C JagetiaM S Baliga
Sep 30, 2004·Cancer Biotherapy & Radiopharmaceuticals·Ganesh JagetiaPonemone Venkatesh
Nov 4, 2004·Integrative Cancer Therapies·Ganesh Chandra JagetiaManjeshwar Shrinath Baliga
Jan 28, 2005·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Ganesh Chandra JagetiaRosi Reddy Veruva
Apr 2, 2005·Journal of Radiation Research·Ganesh Chandra JagetiaPonemone Venkatesh
Jul 1, 2005·Journal of Radiation Research·Anita Krishna, Ashok Kumar
Aug 18, 2005·Phytotherapy Research : PTR·Inder SinghP K Goyal
Jan 6, 2006·Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society for Environmental Toxicology and Cancer·Ganesh Chandra Jagetia, Ponemone Venkatesh
Apr 28, 2006·International Journal of Radiation Biology·Ganesh Chandra Jagetia, V A Venkatesha
Jun 19, 2007·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·M LataR P Tripathi
Aug 26, 1949·Science·H M PattD E Smith
Mar 27, 2009·Basic & Clinical Pharmacology & Toxicology·Ravindra M Samarth, Meenakshi Samarth
Oct 12, 2010·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Manjeshwar Shrinath BaligaPonemone Venkatesh

❮ Previous
Next ❯

Citations

Jul 6, 2013·Mutation Research·Amit AlokN K Chaudhury
Dec 23, 2009·Cancer Biotherapy & Radiopharmaceuticals·Seyed Jalal Hosseinimehr
Sep 27, 2012·Cancer Biotherapy & Radiopharmaceuticals·Dharmendra Kumar Maurya, Thomas Paul Asir Devasagayam
May 16, 2013·BMC Complementary and Alternative Medicine·Tae Gen SonJoong Sun Kim
Dec 19, 2012·Journal of Pharmacy & Bioallied Sciences·Omika KatochKshipra Misra
Apr 12, 2014·International Journal of Molecular Sciences·Jianguo LiFeiyue Fan
Feb 26, 2011·Evidence-based Complementary and Alternative Medicine : ECAM·Priyanka SharmaP K Goyal
Sep 17, 2009·Radiation and Environmental Biophysics·B Santhosh KumarK I Priyadarsini
Jun 9, 2012·Radiation and Environmental Biophysics·D S ThokchomG J Sharma
Dec 2, 2010·Journal of Cancer Research and Therapeutics·Manjeshwar S Baliga, Suresh Rao
Jun 27, 2009·International Journal of Radiation Biology·Joseph F Weiss, Michael R Landauer
Jan 26, 2016·Medicinal Research Reviews·Mohammad Zahid KamranVibha Tandon
Mar 18, 2015·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Jianguo LiQiang Liu
Jun 26, 2009·Evidence-based Complementary and Alternative Medicine : ECAM·Sanghmitra SankhwarM Sarwar Alam
Sep 3, 2008·Journal of Ethnopharmacology·A MuthuramanDhandeep Singh
Dec 14, 2011·Phytotherapy Research : PTR·Joong-Sun KimSung-Ho Kim
Nov 22, 2013·Redox Report : Communications in Free Radical Research·Halina Malgorzata ZbikowskaPaweł Nowak
Jul 18, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Lin-Na LiuYan Han
Sep 12, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Riddhi Sharma
Jun 12, 2013·International Journal of Biological Macromolecules·Jinming ShiWeihong Lu
Sep 27, 2013·BioMed Research International·Gopakumar Gopinathan Nair, Cherupally Krishnan Krishnan Nair
Sep 20, 2011·Free Radical Research·Strayo De, Thomas P A Devasagayam
Apr 28, 2012·Free Radical Research·Yunhai ChuaiJianming Cai
Aug 19, 2014·International Journal of Radiation Biology·Mona A El-GhazalyMohamed T Khayyal
Sep 9, 2011·Radiation Research·K MishraN K Chaudhury
Jun 16, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Joong-Sun KimKwangmo Yang
Mar 11, 2015·International Journal of Radiation Oncology, Biology, Physics·Seo-Young KimYun-Sil Lee
Oct 29, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Hyun Jung KooEun-Hwa Sohn
Jul 16, 2014·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Mohamed T KhayyalMona A El-Ghazaly
Apr 26, 2014·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Runa MasumaMasaaki Kurasaki
Jun 21, 2016·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Bhavesh C VariyaSnehal S Patel
Aug 14, 2015·PloS One·Sripathi M SurebanCourtney W Houchen

❮ Previous
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Methods Mentioned

BETA
chromosomal aberrations

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