PMID: 5910191Apr 22, 1966

Radiosensitization of X chromosome of Chinese hamster cells related to incorporation of 5-bromodeoxyuridine

W C DeweyR M Humphrey


Selective incorporation of 5-bromodeoxyuridine into the late replicating arm of the X chromosome of Chinese hamister cells cultured in vitro caused a selective radiosensization of the arm to ionizing radiation. Radiation damage was observed as chromosomal aberrations, and incorporation was studied by using tritiated 5-bromodeoxyuridine.


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