PMID: 9164684May 1, 1997Paper

Radiosurgery for arteriovenous malformations: the University of Toronto experience

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
C YoungR Ramani

Abstract

From July 1989 to February 1996, 130 patients underwent stereotactic radiosurgery. We report the results of the first 50 patients eligible for a minimum of three years of follow-up. Twenty women and 30 men, (mean age: 37.5 years) were treated by dynamic rotation on a 6 MV linear accelerator. Prior treatment was embolization in seventeen, surgery in three and embolization and surgery in six. All had DSA and enhanced CT scanning, while some had MRI. Forty-seven treatments used a single isodose. Restricting eloquent normal tissue to 15 Gy, margin doses (at 50-90% isodose) were 12 Gy (one patient); 15 Gy (sixteen patients); 20 Gy (31 patients); 25 Gy (two patients). Maximum diameters were: < 1.5 cm (12 patients); < 2.0 cm (nine patients); < 2.5 cm (twelve patients); < 3.0 cm (thirteen patients; 3.0 cm (four patients). Forty-five patients were evaluable at three years, with thirty-nine having angiography. Twenty-five had angiographically confirmed obliterations; two had parenchymal AVMs obliterated but with residual dural components; four had MRI evidence of obliteration (refused angiography). One patient acutely had a seizure; one patient (with hemorrhages, resection, and embolizations preceding two applications of radiosurgery, se...Continue Reading

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Citations

Mar 1, 2007·Neurosurgery·Yuri M Andrade-SouzaMichael L Schwartz
Nov 25, 1998·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·I B Ross, C H Tator
Sep 9, 2004·Journal of Neurosurgery·Gregory J ZipfelWilliam A Friedman
Oct 28, 2011·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·F A ZeilerM West
Aug 28, 2012·Neurosurgery·Patamintita TaeshineetanakulMichael L Schwartz
Oct 28, 2011·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·C HerbertM Martin
Nov 22, 2013·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Matylda MachnowskaTimo Krings
Nov 24, 2006·Journal of Neurosurgery·Yuri M Andrade-SouzaMichael L Schwartz
Jun 2, 2006·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Javad Mirza-AghazadehMichael L Schwartz
May 2, 2012·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·P DaveyB Gillies
May 1, 1997·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·N J Laperriere, M Bernstein
Mar 26, 2014·Neurosurgery·Antonio Di IevaMichael D Cusimano
Dec 19, 2014·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Antonio Di IevaMichael D Cusimano

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