Radiotherapeutical innovations in pediatric solid tumors

Pediatric Blood & Cancer
Jean-Louis HabrandH Roberti

Abstract

There have been considerable technical improvements in radiation therapy for the past two decades. In children affected with cancer, these have been likely overshadowed by concommittant major chemotherapy-based advances, and at least in part ignored and misused. This article outlines principles, technological requirements, and clinical applications of innovations that aim at improving ballistical selectivity (such as conformal, intensity modulation, stereotactic photons, charged particles, and intraoperative therapies), as well as at influencing tumors and normal tissues sensitivity to radiations (such as high LET particles, and altered fractionations).

References

Nov 11, 1991·International Journal of Radiation Oncology, Biology, Physics·R B MarcusR R Million
Aug 1, 1989·American Journal of Clinical Oncology·G E LaramoreL W Davis
Sep 1, 1989·International Journal of Radiation Oncology, Biology, Physics·A P GerbauletD Chassagne
Dec 1, 1995·International Journal of Radiation Oncology, Biology, Physics·J M MichalskiJ A Purdy
Jul 15, 1995·International Journal of Radiation Oncology, Biology, Physics·J DunstC Rübe
Jun 15, 1995·International Journal of Radiation Oncology, Biology, Physics·M H MaorL W Davis
May 1, 1994·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M H PhillipsH R Winn
Nov 1, 1995·Medical Physics·B A Fraass
Jul 1, 1996·International Journal of Radiation Oncology, Biology, Physics·T W BolekJ Graham-Pole
Jan 1, 1996·Frontiers of Radiation Therapy and Oncology·L J Verhey
Jan 1, 1997·Frontiers of Radiation Therapy and Oncology·M Abe
Jan 1, 1997·Clinical Oncology : a Journal of the Royal College of Radiologists·M A Izard
Feb 11, 1998·International Journal of Radiation Oncology, Biology, Physics·S L MeeksR A Zlotecki
Oct 27, 1998·International Journal of Radiation Oncology, Biology, Physics·R M CardinaleR Mohan
Jun 23, 2000·International Journal of Radiation Oncology, Biology, Physics·E B HugJ E Munzenrider
Jun 23, 2000·International Journal of Radiation Oncology, Biology, Physics·D A Haas-KoganK K Matthay
Jan 9, 2001·Seminars in Radiation Oncology·M T MunleyG C Bentel
Mar 10, 2001·International Journal of Radiation Oncology, Biology, Physics·S NagUNKNOWN American Brachytherapy Society
Aug 23, 2001·International Journal of Radiation Oncology, Biology, Physics·N OyaM Hiraoka
Oct 13, 2001·International Journal of Radiation Oncology, Biology, Physics·S S DonaldsonUNKNOWN Children's Oncology Group Soft Tissue Sarcoma Committee (formely Intergroup Rhabdomyosarcoma Group) representing the Childre
Apr 18, 2002·International Journal of Radiation Oncology, Biology, Physics·Eugen B HugJohn E Munzenrider
Jul 16, 2002·Seminars in Radiation Oncology·Eli Glatstein
Oct 16, 2002·International Journal of Radiation Oncology, Biology, Physics·Raymond MiralbellUwe Schneider
Feb 27, 2003·Clinical Oncology : a Journal of the Royal College of Radiologists·M Goitein, M Jermann

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Citations

Nov 3, 2005·Nature Clinical Practice. Oncology·Lyndon M GommersallPatrick Duffy
Nov 1, 2005·International Journal of Radiation Oncology, Biology, Physics·Susanne OertelJuergen Debus
Jul 17, 2016·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·C Demoor-GoldschmidtV Bernier
May 10, 2017·Pediatric Blood & Cancer·Giorgio PerilongoBerta Jereb

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