PMID: 3771313Nov 1, 1986Paper

Radiotherapy of Kaposi's sarcoma

International Journal of Radiation Oncology, Biology, Physics
C R HamiltonA R Harwood

Abstract

Between 1958 and 1983, 91 patients with Kaposi's sarcoma were referred to the Princess Margaret Hospital. Eight patients received no specific therapy immediately following their first assessment. Twenty-seven patients were treated by local field radiotherapy, of whom 17 entered complete remission and 6 have remained relapse-free. Fifty-six patients received extended field radiotherapy, usually a single fraction of 8 Gy megavoltage gamma-ray or photon therapy; 38 achieved completed remission, and 24 have remained relapse-free for a median duration of 3 years. The actuarial relapse-free survival for patients treated by local versus extended field radiotherapy significantly favors the extended field technique although the rates of relapse after complete remission has been achieved appear similar. Immunosuppression was present in 12 patients prior to the diagnosis of Kaposi's sarcoma; these patients had a similar response rate to radiation therapy to those who were not known to be immunosuppressed. A rationale for management, and radiation technique and dose are discussed. It is concluded that radiotherapy is an effective treatment for most forms of Kaposi's sarcoma.

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Citations

Jan 1, 1991·Journal of Cancer Research and Clinical Oncology·R KrausC Streffer
Nov 1, 1995·Clinics in Dermatology·R G Parker
Dec 13, 2006·Medicina clínica·José Barquero-RomeroJuan Pimentel Leo
Aug 9, 2011·Annals of Surgical Oncology·Pietro CuratoloMaria Grazia Bernengo
Jan 27, 2010·Environmental Health Perspectives·Erik R SvendsenWilfried J J Karmaus
Feb 2, 2013·Rare Tumors·Juliette ThariatRobert C Miller
Mar 21, 2009·Journal of Cutaneous Medicine and Surgery·David HauerstockTe Vuong
Sep 22, 2006·Journal of the European Academy of Dermatology and Venereology : JEADV·L BrambillaV Boneschi
Jul 29, 2005·JAAPA : Official Journal of the American Academy of Physician Assistants·Ellen Joffe, Louis D Dubilier
May 17, 2019·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Celeste LebbeUNKNOWN European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organisation for Rese
Oct 1, 1996·Hematology/oncology Clinics of North America·P S Swift

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