PMID: 9539565Apr 16, 1998Paper

Radiotherapy options for localized prostate cancer based upon pretreatment serum prostate-specific antigen levels and biochemical control: a comprehensive review of the literature

International Journal of Radiation Oncology, Biology, Physics
F A ViciniA A Martinez

Abstract

To review all the available radiotherapy (RT) literature on localized prostate cancer treatment where serum prostate-specific antigen (PSA) levels were used to both stratify patients and evaluate outcome and determine if any conclusions can be reached regarding an optimal radiotherapeutic management for this disease. A MEDLINE search was conducted to obtain all articles in English on prostate cancer treatment employing RT from 1986-1997. Studies were considered eligible for review only if they met all the following criteria: 1) pretreatment PSA values were recorded and grouped for subsequent evaluation, 2) posttreatment PSA values were continuously monitored, 3) definitions of biochemical control were stated, and 4) the median follow-up was given. Of the 246 articles identified, only 20 met the inclusion criteria; 4 using conformal external beam RT, 8 using conventional external beam RT, and 8 using interstitial brachytherapy (4 using a permanent implant alone, 3 combining external beam RT with a permanent implant, and 1 combining a conformal temporary interstitial implant boost with external beam RT). No studies using neutrons (with or without external beam RT) or androgen deprivation (combined with external beam RT) were iden...Continue Reading

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Citations

Dec 20, 1999·Seminars in Roentgenology·S R Potter, A W Partin
Dec 6, 2000·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·L E BlankK Koedooder
Nov 25, 2003·International Journal of Radiation Oncology, Biology, Physics·Deborah KubanIsaac Rosen
Mar 31, 1999·International Journal of Radiation Oncology, Biology, Physics·F A ViciniA A Martinez
May 29, 1999·International Journal of Radiation Oncology, Biology, Physics·F A ViciniA Martinez
Oct 1, 2006·Journal of Medical Physics·K R Das
Sep 15, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Bradley R PietersAeilko H Zwinderman
Jul 20, 1999·The Journal of Urology·N N Stone, R G Stock
Aug 30, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Shabbir M H AlibhaiMurray D Krahn

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