Radiotracer-guided thoracoscopic resection is a cost-effective technique for the evaluation of subcentimeter pulmonary nodules

The Annals of Thoracic Surgery
Eric L GroganThomas M Daniel

Abstract

Excisional biopsy of small subcentimeter pulmonary nodules can be difficult using standard thoracoscopic techniques and may require thoracotomy. Radiotracer-guided thoracoscopic resection (RGTR) was developed to facilitate resection of intraparenchymal subcentimeter pulmonary nodules. Decision analysis, used to model cost and effectiveness, is useful to compare treatment options. We hypothesize that RGTR strategy is more cost-effective compared with thoracotomy for subcentimeter pulmonary nodules. The cost-effectiveness of RGTR versus thoracotomy for evaluating highly suspicious subcentimeter pulmonary nodules was examined with a decision analysis model (Fig 1). A 40-patient institutional cohort who underwent RGTR was used to estimate probabilities and costs of the two treatment options within the model. Effectiveness was estimated using 5-year, stage-specific cancer survival and population survival curves. The Society of Thoracic Surgeons General Thoracic Database was queried obtaining mortality estimates for thoracotomy and thoracoscopic wedge resections. These were used to adjust the 5-year survival estimates of patients with benign disease. Sensitivity analyses determined model robustness and the thresholds at which the mos...Continue Reading

References

Aug 1, 1994·AJR. American Journal of Roentgenology·F X LenglingerW Artmann
Oct 1, 1993·The Annals of Thoracic Surgery·M J MackT E Acuff
Jan 1, 1997·Radiology·R F MundenL U Le
Sep 20, 2002·The Annals of Thoracic Surgery·Larkin J DanielsThomas A D'Amico
Oct 21, 2003·The Journal of Thoracic and Cardiovascular Surgery·Shoji SakiyamaYasumasa Monden
Apr 28, 2004·The Annals of Thoracic Surgery·Thomas M DanielSpencer B Gay
Jan 22, 2005·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun
Sep 23, 2006·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Dong Ming XuRob van Klaveren
Sep 26, 2006·The Annals of Thoracic Surgery·Brendon M StilesThomas M Daniel
Oct 27, 2006·The New England Journal of Medicine·UNKNOWN International Early Lung Cancer Action Program InvestigatorsOlli S Miettinen
Dec 5, 2006·The Journal of Thoracic and Cardiovascular Surgery·Paul C LeeNasser K Altorki
Mar 8, 2007·JAMA : the Journal of the American Medical Association·Peter B BachColin B Begg
Aug 2, 2007·JAMA : the Journal of the American Medical Association·Claudia I HenschkeOlli S Miettinen
Oct 5, 2007·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alessandro GonfiottiAlberto Janni

❮ Previous
Next ❯

Citations

Mar 29, 2012·General Thoracic and Cardiovascular Surgery·Luca BertolacciniDonatella Ghirardo
Mar 1, 2012·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Chad V PecotPierre P Massion
Jun 18, 2015·Thorax·M E J CallisterUNKNOWN British Thoracic Society Standards of Care Committee
Jul 4, 2012·The Annals of Thoracic Surgery·Chi-Fu Jeffrey Yang, Thomas A D'Amico
May 25, 2010·The Annals of Thoracic Surgery·Eric L GroganPierre P Massion
Nov 26, 2010·The Annals of Thoracic Surgery·Massimo BellomiLorenzo Spaggiari

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.