Radiotracer Imaging of Peripheral Vascular Disease

Journal of Nuclear Medicine Technology
Mitchel R StacyAlbert J Sinusas

Abstract

Peripheral vascular disease (PVD) is an atherosclerotic disease affecting the lower extremities, resulting in skeletal muscle ischemia, intermittent claudication, and, in more severe stages of disease, limb amputation and death. The evaluation of therapy in this patient population can be challenging, as the standard clinical indices are insensitive to assessment of regional alterations in skeletal muscle physiology. Radiotracer imaging of the lower extremities with techniques such as PET and SPECT can provide a noninvasive quantitative technique for the evaluation of the pathophysiology associated with PVD and may complement clinical indices and other imaging approaches. This review discusses the progress in radiotracer-based evaluation of PVD and highlights recent advancements in molecular imaging with potential for clinical application.

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Citations

Nov 5, 2016·European Journal of Nuclear Medicine and Molecular Imaging·Geert HendrikxFelix M Mottaghy
Mar 10, 2015·Annals of Nuclear Medicine·Mitchel R StacyAlbert J Sinusas
Jan 16, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Yiu Ming Khor, Sharmila Dorbala
Aug 20, 2019·JACC. Cardiovascular Imaging·Sanjay DivakaranMarcelo F Di Carli

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