Rafting with the IL-12 receptor.

Blood
Daniel W McVicar

Abstract

In this issue of Blood, Kondadasula and colleagues provide important clues for understanding successful cancer immunotherapy by demonstrating an intriguing mechanism through which CD16 synergizes with IL-12 to induce interferon-gamma (IFN-gamma) production by NK cells.

References

Oct 9, 2002·The Journal of Clinical Investigation·Robin PariharWilliam E Carson
Oct 27, 2005·Blood·John R OrtaldoHoward A Young

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