Raman fingerprints of amyloid structures

Chemical Communications : Chem Comm
Jessica D Flynn, Jennifer C Lee

Abstract

Structural differences in pathological and functional amyloid fibrils have been investigated by Raman microspectroscopy. Second-derivative analyses of amide-I and amide-III bands distinguish parallel in-register β-sheets from a β-solenoid. Further, spatially resolved Raman spectra reveal molecular heterogeneity in amyloid structures.

References

Aug 30, 1983·Biochemical and Biophysical Research Communications·H Susi, D M Byler
Sep 16, 2005·Pigment Cell Research·Alexander C TheosMichael S Marks
Jun 8, 2006·Annual Review of Biochemistry·Fabrizio Chiti, Christopher M Dobson
Aug 12, 2006·Fungal Genetics and Biology : FG & B·Laura Benkemoun, Sven J Saupe
Jun 19, 2007·The Journal of Biological Chemistry·Min ChenRalf Langen
Apr 11, 2008·Clinical Science·Esther M M OoiGerald F Watts
Aug 12, 2009·Proceedings of the National Academy of Sciences of the United States of America·Ryan P McGlincheyReed B Wickner
Dec 15, 2010·The Journal of Biological Chemistry·Ryan P McGlincheyReed B Wickner
Apr 2, 2011·The Journal of Biological Chemistry·Frank ShewmakerReed B Wickner
May 9, 2014·Biochemistry·Michel de MessieresJennifer C Lee
Jun 24, 2014·Chembiochem : a European Journal of Chemical Biology·Ryan P McGlincheyJennifer C Lee
Mar 29, 2016·Nature Structural & Molecular Biology·Marcus D TuttleChad M Rienstra
Jun 30, 2016·Journal of the American Chemical Society·Michael T ColvinRobert G Griffin
Jul 30, 2016·Proceedings of the National Academy of Sciences of the United States of America·Marielle Aulikki WältiRoland Riek
Aug 10, 2017·Biochemistry·Robert SilversRobert G Griffin
Sep 9, 2017·Science·Lothar GremerGunnar F Schröder
Dec 2, 2017·The Journal of Biological Chemistry·Jessica D FlynnJennifer C Lee

❮ Previous
Next ❯

Citations

Oct 30, 2018·Angewandte Chemie·Jessica D FlynnJennifer C Lee
Apr 12, 2020·The Journal of Biological Chemistry·Dexter N Dean, Jennifer C Lee
Aug 8, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Martynas TalaikisGediminas Niaura
Dec 16, 2020·Nature Communications·Dvir GurDavid M Parichy
Feb 13, 2021·ACS Nano·Ana M GarciaSilvia Marchesan
Feb 1, 2021·The Journal of Biological Chemistry·Dexter N Dean, Jennifer C Lee
Apr 10, 2021·The Journal of Physical Chemistry. B·Sydney O Shuster, Jennifer C Lee
May 23, 2021·Movement Disorders : Official Journal of the Movement Disorder Society·Dexter N Dean, Jennifer C Lee
Jun 30, 2021·Current Opinion in Chemical Biology·Matthew D Watson, Jennifer C Lee
Jul 23, 2021·Protein Expression and Purification·Dexter N Dean, Jennifer C Lee
Oct 30, 2019·ACS Chemical Neuroscience·George DevittSumeet Mahajan
Aug 10, 2021·International Journal of Biological Macromolecules·Sudeshna Ghosh, Sandeep Verma
Dec 5, 2021·The FEBS Journal·Joëlle A J HousmansFrederic Rousseau

❮ Previous
Next ❯

Methods Mentioned

BETA
transmission electron microscopy
circular dichroism
Raman microspectroscopy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.