PMID: 10006Nov 1, 1976

Raman ph profiles for nucleic acid constituents. II. 5'-AMP and 5'-GMP ribonucleotides

Biochimica Et Biophysica Acta
T O'ConnorW M Scovell

Abstract

Raman spectra of aqueous solutions of 5'-AMP and 5'-GMP have been recorded as a function of pH. Band intensities and frequencies have been monitored to determine bands which may be considered as diagnostic for the concentration and the pK of the solution species. Quantitative band intensity measurements indicate only a selected number of bands can be considered as diagnostic of the base or the secondary phosphate proton dissociation. The utility of the pH profiles derived from specific band intensity variations for 5'-AMP is discussed in terms of the effect of acidification on solution characteristics of polyadenylic acid.

References

Dec 15, 1962·Proceedings of the National Academy of Sciences of the United States of America·M GELLERTD R DAVIES

Citations

Aug 20, 2002·Proceedings of the National Academy of Sciences of the United States of America·K Mark ParnellScott A Strobel
Mar 1, 1979·Nucleic Acids Research·W M ScovellA D Broom
Aug 1, 1980·Journal of Microscopy·A T Sumner

Related Concepts

5'-Adenylic Acid
Guanine Nucleotides
Hydrogen-Ion Concentration
Scattering, Radiation
Spectrometry

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