PMID: 11320044Apr 26, 2001Paper

Randomised controlled study of oral erythromycin for treatment of gastrointestinal dysmotility in preterm infants

Archives of Disease in Childhood. Fetal and Neonatal Edition
P C NgA F Cheng

Abstract

To evaluate the effectiveness of oral erythromycin as a prokinetic agent for the treatment of moderately severe gastrointestinal dysmotility in preterm very low birthweight infants. A prospective, double blind, randomised, placebo controlled study in a tertiary referral centre of a university teaching hospital was conducted on 56 preterm infants (< 1500 g) consecutively admitted to the neonatal unit. The infants were randomly allocated by minimisation to receive oral erythromycin (12.5 mg/kg, every six hours for 14 days) or an equivalent volume of placebo solution (normal saline) if they received less than half the total daily fluid intake or less than 75 ml/kg/day of milk feeds by the enteral route on day 14 of life. The times taken to establish half, three quarters, and full enteral feeding after the drug treatment were compared between the two groups. Potential adverse effects of oral erythromycin and complications associated with parenteral nutrition were assessed as secondary outcomes. Twenty seven and 29 infants received oral erythromycin and placebo solution respectively. The times taken to establish half, three quarters, and full enteral feeding after the drug treatment were significantly shorter in the group receiving ...Continue Reading

References

Jul 1, 1979·Digestive Diseases and Sciences·G VantrappenJ Hellemans
Jan 1, 1992·Journal of Pediatric Gastroenterology and Nutrition·J B Gouyon
Jul 1, 1990·Journal of Pediatric Gastroenterology and Nutrition·C Di LorenzoP E Hyman
Apr 12, 1990·The New England Journal of Medicine·J JanssensR Bouillon
Jul 1, 1995·Gastroenterology·S Bruley des VarannesJ P Galmiche
Sep 1, 1994·The Pediatric Infectious Disease Journal·J B GouyonJ Badoual
Oct 1, 1994·The British Journal of Surgery·M A Pilot
Aug 1, 1994·Archives of Disease in Childhood·R G GrundyJ P Evans
Sep 1, 1994·Archives of Disease in Childhood. Fetal and Neonatal Edition·D E SimkissI W Booth
Apr 1, 1994·Acta Paediatrica Japonica; Overseas Edition·M KubotaA Nishida
Jul 1, 1993·The British Journal of Surgery·A D HillT P Hennessy
Jan 1, 1993·Biology of the Neonate·T TomomasaT Kuroume
Apr 1, 1997·Journal of Pediatric Gastroenterology and Nutrition·S CucchiaraG Salvia
Apr 1, 1997·Journal of Paediatrics and Child Health·P C NgK L Cheung
Apr 16, 1998·Archives of Disease in Childhood. Fetal and Neonatal Edition·A J LyonP W Ross
Jun 6, 1998·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·C Mathis, C H Malbert
Apr 9, 1999·Archives of Disease in Childhood. Fetal and Neonatal Edition·B J StensonA J Lyon

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Citations

Mar 18, 2009·Pediatric Surgery International·Asma RazzaqSalman Ali
Jul 1, 2004·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Eman Abu-GharbiehFabrizio De Ponti
Oct 11, 2005·Acta Paediatrica. Supplement·Josef Neu, Liyan Zhang
Sep 10, 2003·Journal of Pediatric Gastroenterology and Nutrition·Adel A ElHennawyCarol Lynn Berseth
Oct 29, 2003·Journal of Pediatric Gastroenterology and Nutrition·Steven Chin-Yuen NgSeng-Hock Quak
Dec 24, 2010·Current Opinion in Pediatrics·Hugh S Lam, Pak C Ng
May 19, 2005·Archives of Disease in Childhood. Fetal and Neonatal Edition·S PatoleD Doherty
May 14, 2011·Journal of Perinatology : Official Journal of the California Perinatal Association·T GokmenU Dilmen
Jan 17, 2012·Journal of Pediatric Surgery·Shawn J RangelUNKNOWN 2011 American Pediatric Surgical Association Outcomes and Clinical Trials Committee
Oct 5, 2007·Early Human Development·Josef Neu
Jun 2, 2006·The Journal of Pediatrics·Pracha NuntnarumitSuppawat Boonkasidecha
Nov 10, 2005·Early Human Development·Yvan VandenplasBruno Hauser
Apr 11, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Tulin GokmenUgur Dilmen
Mar 10, 2005·The Annals of Pharmacotherapy·Michael F ChicellaJames E Dice
Mar 11, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Selim SancakFahri Ovali
Oct 13, 2006·Journal of Perinatology : Official Journal of the California Perinatal Association·H AlyN El-Badry
Jul 23, 2008·The Cochrane Database of Systematic Reviews·Eugene Ng, Vibhuti S Shah
Aug 14, 2019·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Liz Febo-RodriguezRobert J Shulman
Jan 19, 2019·The Cochrane Database of Systematic Reviews·Malene Plejdrup HansenChris B Del Mar
Dec 26, 2001·Journal of Pediatric Gastroenterology and Nutrition·Ajay Kaul
Sep 11, 2018·Paediatric Drugs·Steven L Ciciora, Frederick W Woodley
Dec 20, 2019·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Katja KovacicMiguel Saps
Sep 16, 2004·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Shawna M Henry
Jun 26, 2021·Pediatrics and Neonatology·Pattarapan SukwuttichaiNawaporn Vimolsarawong

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