PMID: 3322351Dec 1, 1987Paper

Randomised crossover trial of rate responsive Activitrax and conventional fixed rate ventricular pacing

British Heart Journal
D P LipkinD M Krikler

Abstract

Atrial tracking pacemakers may improve exercise capacity and symptoms because they maintain atrioventricular synchrony and preserve the physiological response of heart rate to exercise. A rate responsive pacemaker which reacts to physical activity may be effective in patients with sinus node disease who are unsuitable for VDD pacing. At least three months after implant a double blind randomised short and long term crossover study was performed in ten patients with complete heart block: block was present at rest and during exercise on a modified Bruce protocol. Symptoms were assessed on a visual analogue scale and exercise capacity (maximal oxygen consumption and anaerobic threshold) was measured during rate responsive (peak rate 125/min) and conventional fixed rate (VVI) pacing (70/min). One month after randomisation treadmill exercise was performed. The mode was then changed to the other pacing mode and exercise was repeated three hours later. After another month the process was repeated but in the reverse order. During long term assessment there was subjective improvement in the sensation of breathlessness with rate responsive pacing. During short term assessment maximal oxygen consumption increased and the benefit was mainta...Continue Reading

References

Nov 1, 1986·Pacing and Clinical Electrophysiology : PACE·F W LindemansP A Chevalier
Jan 1, 1985·Pacing and Clinical Electrophysiology : PACE·D P HumenG J Klein
Jan 1, 1985·Pacing and Clinical Electrophysiology : PACE·B E KristenssonL Rydén
Sep 1, 1985·British Heart Journal·D P LipkinP A Poole-Wilson
Nov 1, 1984·Pacing and Clinical Electrophysiology : PACE·A WirtzfeldH D Liess
Aug 1, 1983·British Heart Journal·E J PerrinsR Sutton
Feb 26, 1983·British Medical Journal·R M DonaldsonA F Rickards
Feb 1, 1965·The American Journal of Cardiology·P SAMETS LEVINE

❮ Previous
Next ❯

Citations

Mar 1, 1993·Clinical Cardiology·D KatritsisA J Camm
Apr 1, 1992·British Heart Journal·A W Nathan, D W Davies
Aug 1, 1993·Pacing and Clinical Electrophysiology : PACE·N TreeseJ Meyer
Sep 1, 1993·Pacing and Clinical Electrophysiology : PACE·D T Connelly
Jul 1, 1993·Pacing and Clinical Electrophysiology : PACE·M E CabreraJ Liebman
Nov 1, 1994·Pacing and Clinical Electrophysiology : PACE·S SinhaJ L Caplin
Nov 1, 1994·Pacing and Clinical Electrophysiology : PACE·J LuklP Heinc
Sep 23, 1998·Pacing and Clinical Electrophysiology : PACE·R G HaennelE Busse
Aug 1, 1992·Pacing and Clinical Electrophysiology : PACE·C P Lau
Sep 4, 2007·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Mark H Schoenfeld
Jun 1, 1993·American Heart Journal·S S Barold, R S Sanders
Mar 1, 1991·Progress in Cardiovascular Diseases·M W Baig, E J Perrins
Mar 1, 1989·American Heart Journal·J D Kugler, D A Danford
Mar 10, 2000·Cardiology Clinics·S K Leung, C P Lau
Mar 1, 1994·Journal of the American Geriatrics Society·D E Bush, T E Finucane

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.