PMID: 9651260Jul 4, 1998Paper

Randomised trial of heroin maintenance programme for addicts who fail in conventional drug treatments

BMJ : British Medical Journal
T V PernegerA Mino

Abstract

To evaluate an experimental heroin maintenance programme. Randomised trial. Outpatient clinic in Geneva, Switzerland. Heroin addicts recruited from the community who were socially marginalised and in poor health and had failed in at least two previous drug treatments. Patients in the experimental programme (n=27) received intravenous heroin and other health and psychosocial services. Control patients (n=24) received any other conventional drug treatment (usually methadone maintenance). Self reported drug use, health status (SF-36), and social functioning. 25 experimental patients completed 6 months in the programme, receiving a median of 480 mg of heroin daily. One experimental subject and 10 control subjects still used street heroin daily at follow up (difference 44%; 95% confidence interval 16% to 71%). Health status scores that improved significantly more in experimental subjects were mental health (0.58 SD; 0.07 to 1.10), role limitations due to emotional problems (0.95 SD; 0.11 to 1.79), and social functioning (0.65 SD; 0.03 to 1.26). Experimental subjects also significantly reduced their illegal income and drug expenses and committed fewer drug and property related offences. There were no benefits in terms of work, housin...Continue Reading

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