Randomized clinical trial of intracutaneously versus transcutaneously sutured ileostomy to prevent stoma-related complications (ISI trial)

The British Journal of Surgery
M F SierISI trial study group

Abstract

Ileostomy construction is a common procedure but can be associated with morbidity. The stoma is commonly secured to the skin using transcutaneous sutures. It is hypothesized that intracutaneous sutures result in a tighter adherence of the peristomal skin to the stoma plate to prevent faecal leakage. The study aimed to compare the effect of intracutaneous versus transcutaneous suturing of ileostomies on faecal leakage and quality of life. This randomized trial was undertaken in 11 hospitals in the Netherlands. Patients scheduled to receive an ileostomy for any reason were randomized to intracutaneous or transcutaneous suturing (IC and TC groups respectively). The primary outcome was faecal leakage. Secondary outcomes were stoma-related quality of life and costs of stoma-related materials and reinterventions. Between April 2011 and February 2016, 339 patients were randomized to the IC (170) or TC (169) group. Leakage rates were higher in the IC than in the TC group (52·4 versus 41·4 per cent respectively; risk difference 11·0 (95 per cent c.i. 0·3 to 21·2) per cent). Skin irritation rates were high (78·2 versus 72·2 per cent), but did not differ significantly between the groups (risk difference 6·1 (95 per cent c.i. -3·2 to 15·10...Continue Reading

References

Jun 30, 1998·Diseases of the Colon and Rectum·E M AdangC G Baeten
Jul 22, 1999·American Journal of Surgery·P T PhangB T Gemlo
Dec 29, 1999·Diseases of the Colon and Rectum·J J ParkH Abcarian
Jun 5, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·O. HallböökR. Sjödahl
Aug 17, 2004·Digestive Surgery·R BakxJ J B van Lanschot
Jan 25, 2005·Digestive Surgery·S A García-BotelloS Lledó
Apr 30, 2005·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·I RobertsonA Macdonald
Oct 13, 2005·Health and Quality of Life Outcomes·Luis PrietoKristian Juul
Oct 18, 2005·American Journal of Surgery·Christopher BellThomas Anthony
Nov 1, 2005·Journal of the American College of Surgeons·Orit Kaidar-PersonSteven D Wexner
Aug 4, 2007·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J CottamA Blackman
Jan 30, 2009·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·G F GiannakopoulosM A Cuesta
Jul 17, 2009·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J Shabbir, D C Britton
Oct 3, 2009·British Journal of Nursing : BJN·Caroline RedmondTheresa Parker
Oct 27, 2010·The British Journal of Dermatology·G B JemecR G Sibbald
Nov 16, 2010·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·UNKNOWN Ostomy Guidelines Task ForceRonald Palmer
Feb 4, 2012·International Journal of Colorectal Disease·H A Formijne JonkersE C J Consten
Sep 7, 2012·BMJ : British Medical Journal·Marion K CampbellUNKNOWN CONSORT Group

❮ Previous
Next ❯

Citations

Feb 29, 2020·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·T O VilzB Stoffels
Mar 4, 2020·Techniques in Coloproctology·G PellinoUNKNOWN Italian Society of Colorectal Surgery SICCR

❮ Previous
Next ❯

Software Mentioned

SPSS®
Ostomy Skin Tool

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
R M AbeggD J Lips
Digestive Surgery
Roel BakxJ Jan B van Lanschot
The European Journal of Surgery = Acta Chirurgica
E Carlsen, A B Bergan
© 2022 Meta ULC. All rights reserved