Randomized clinical trial of transcutaneous electrical posterior tibial nerve stimulation versus lateral internal sphincterotomy for treatment of chronic anal fissure

International Journal of Surgery
Tamer YoussefMohamed Farid

Abstract

The objective of this study was to evaluate the efficacy of transcutaneous electrical posterior tibial nerve stimulation in treatment of patients with chronic anal fissure and to compare it with the conventional lateral internal sphincterotomy. Consecutive patients with chronic anal fissure were randomly allocated into two treatment groups: transcutaneous electrical posterior tibial nerve stimulation group and lateral internal sphincterotomy group. The primary outcome measures were number of patients with clinical improvement and healed fissure. Secondary outcome measures were complications, VAS pain scores, Wexner's constipation and Peascatori anal incontinence scores, anorectal manometry, and quality of life index. Seventy-three patients were randomized into two groups of 36 patients who were subjected to transcutaneous electrical nerve stimulation and 37 patients who underwent lateral internal sphincterotomy. All (100%) patients in lateral internal sphincterotomy group had clinical improvement at one month following the procedure in contrast to 27 (75%) patients in transcutaneous electrical nerve stimulation group. Recurrence of anal fissure after one year was reported in one (2.7%) and 11 (40.7%) patients in lateral interna...Continue Reading

Associated Clinical Trials

References

May 1, 1992·Diseases of the Colon and Rectum·M PescatoriA Mentasti
Jul 1, 1984·Diseases of the Colon and Rectum·T C Hsu, J M MacKeigan
Mar 28, 1996·The New England Journal of Medicine·M A Testa, D C Simonson
Jun 1, 1996·Diseases of the Colon and Rectum·F AgachanS D Wexner
Apr 1, 1996·Diseases of the Colon and Rectum·J Garcia-AguilarR D Madoff
Jan 4, 1998·Diseases of the Colon and Rectum·D R Littlejohn, G L Newstead
Dec 10, 2002·Journal of the Royal Army Medical Corps·J P GarnerD P Edwards
Sep 19, 2003·International Journal of Colorectal Disease·Adriano TocchiStefania Brozzetti
Dec 3, 2004·ANZ Journal of Surgery·Joe J TjandraKlaus Matzel
Apr 7, 2006·Diseases of the Colon and Rectum·B Bülent MenteşMehmet Oguz
Apr 1, 2009·Diseases of the Colon and Rectum·Ezio FallettoUNKNOWN GINS (Italian Group for Sacral Neuromodulation)
Jul 22, 2009·International Journal of Colorectal Disease·Jim S KhanAndrew J G Miles
Jun 5, 2010·International Journal of Colorectal Disease·Veronique VittonFrançois Mion
Dec 17, 2010·World Journal of Gastrointestinal Surgery·Aaron PohFrancis Seow-Choen
Jul 13, 2013·International Journal of Colorectal Disease·Burcu AltunrendeEdip Erdal Yilmaz
Dec 7, 2013·International Journal of Colorectal Disease·Yusuke KinugasaKenichi Sugihara
Jan 30, 2015·Current Urology Reports·Priyanka GuptaKenneth M Peters

❮ Previous
Next ❯

Citations

Apr 7, 2017·Iranian Journal of Nursing and Midwifery Research·Maryam RezaeyanAshraf Direkvand-Moghadam
Aug 11, 2017·Techniques in Coloproctology·R L NelsonA Yeboah-Sampong
Jul 18, 2020·United European Gastroenterology Journal·Ferdinando D'AmicoLaurent Peyrin-Biroulet
Sep 12, 2017·Techniques in Coloproctology·A Muñoz-DuyosS Delgado-Rivilla
Feb 6, 2020·Neuromodulation : Journal of the International Neuromodulation Society·Bridget R Southwell
Jun 17, 2021·International Journal of Colorectal Disease·Konstantinos PerivoliotisKonstantinos Tepetes

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved