Randomized clinical trials in soft tissue sarcoma

Surgical Oncology Clinics of North America
Steven C Katz, Murray F Brennan

Abstract

Soft tissue sarcomas (STS) are rare, but potentially lethal, extraskeletal mesenchymal neoplasms. It is estimated that approximately 12,000 cases of STS are reported annually in the United States, with 3,500 STS deaths. Few randomized controlled trials (RCTs) have been conducted since the previous issue of this publication. The current understanding of STS biology and, hence, ability to provide safe, effective therapy is predicated upon seminal trials performed in the 1980s and 1990s. The authors briefly summarize the trials presented in the previous issue and then critically assess the more recent publications that have addressed the management of STS.

References

Sep 1, 1983·Cancer Treatment Reviews·R Stuart-HarrisE Wiltshaw
Jul 1, 1993·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·K AntmanD L Trump
Mar 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P W PistersM F Brennan
Jan 24, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J C YangS A Rosenberg
Mar 7, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S FrustaciP Picci
May 30, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E GortzakUNKNOWN E.O.R.T.C. Soft Tissue Bone Sarcoma Group and the National Cancer Institute of Canada Clinical Trials Group/Canadian Sarcoma
Oct 24, 2002·American Journal of Clinical Oncology·Roberto PetrioliGuido Francini
Jun 11, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Aileen M DavisUNKNOWN NCI Canada Clinical Trial Group Randomized Trial
Jun 25, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S BonvalotD Elias
Jul 20, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Paul LoriganUNKNOWN European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Study
Oct 3, 2008·Annals of Surgical Oncology·Robert J CanterMurray F Brennan
Feb 9, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Alessandro GronchiPiero Picci

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Citations

Sep 2, 2014·Journal of Surgical Oncology·Max VaynrubLawrence R Menendez
Jul 15, 2015·The Journal of Surgical Research·Noah K YuenRobert J Canter
Jun 10, 2011·Current Opinion in Oncology

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