PMID: 9179835Oct 1, 1996Paper

Randomized controlled pilot trial of a hand-held patient-oriented, insulin regimen optimizer

Medical Informatics = Médecine Et Informatique
R R HolmanJ L Nealon

Abstract

A robust, hand-held, patient-oriented insulin regimen optimizer (POIRO) has been developed. Relevant information is entered by selecting appropriate items from choices displayed on a touch-sensitive screen rather than a conventional keyboard. All data items are recorded, together with their time and date of entry, and may be recalled at any time with glucose values displayed graphically to provide an overview of glycaemic control. When requested, an integral, hybrid, statistical and rule-based expert system program uses all available data to suggest an optimum insulin dose within physician determined, pre-set limits. POIRO has been formally evaluated in a randomized crossover pilot trial, comparing two 3 week periods with and without decision support, in six patients with type 1 diabetes. Mean (SE) pre-prandial blood glucose levels were significantly lower during the period when decision support was available (7.5 (0.4) versus 8.9 (0.4) mmol/l, p = 0.015) with no increase in the frequency or severity of hypoglycaemia. The device, which was well received by the patients, may offer a relatively inexpensive method of providing expert diabetic advice at a distance. The persistence of improved glycaemic control, even after decision ...Continue Reading

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Citations

Sep 24, 2005·Journal of Medical Systems·Craig E KuziemskyRaymond C Leung
Jul 9, 2002·Computer Methods and Programs in Biomedicine·Jürgen SchrezenmeirPeter Papazov
Mar 13, 1999·International Journal of Medical Informatics·S MontaniM Stefanelli
Jun 19, 2002·Biochimica Et Biophysica Acta·C L SayasF Wandosell
Jul 27, 2001·Diabetes Technology & Therapeutics·E Colloff
Mar 2, 2005·Diabetes Technology & Therapeutics·Howard ZisserCamelia Owens
Aug 20, 2011·Journal of the American Medical Informatics Association : JAMIA·K Ann McKibbonPavel S Roshanov
Jan 1, 1997·Medical Informatics = Médecine Et Informatique·E D Lehmann
Nov 9, 2007·Diabetes Research and Clinical Practice·Kun-Ho Yoon, Hee-Seung Kim
May 1, 2013·Pediatric Diabetes·Donna S Eng, Joyce M Lee
Feb 24, 2001·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·R BellazziC Cobelli
Nov 30, 2019·Journal of Evaluation in Clinical Practice·Pengli JiaMingming Zhang
Jan 1, 1997·Medical Informatics = Médecine Et Informatique·E D Lehmann

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