Randomized Controlled Trial Evaluating Dialkylcarbamoyl Chloride Impregnated Dressings for the Prevention of Surgical Site Infections in Adult Women Undergoing Cesarean Section

Surgical Infections
Paweł Jan StanirowskiWłodzimierz Sawicki

Abstract

Surgical site infections (SSI) occur in 1.8%-9.2% of women undergoing cesarean section (CS) and lead to greater morbidity rates and increased treatment costs. The aim of the study was to evaluate the efficacy and cost-effectiveness of dialkylcarbamoyl chloride (DACC) impregnated dressings to prevent SSI in women subject to CS. Randomized, controlled trial was conducted at the Mazovian Bródno Hospital, a tertiary care center performing approximately 1300 deliveries per year, between June 2014 and April 2015. Patients were randomly allocated to receive either DACC impregnated dressing or standard surgical dressing (SSD) following skin closure. In order to analyze cost-effectiveness of the selected dressings in the group of patients who developed SSI, the costs of ambulatory visits, additional hospitalization, nursing care, and systemic antibiotic therapy were assessed. Independent risk factors for SSI were determined by multivariable logistic regression. Five hundred and forty-three women undergoing elective or emergency CS were enrolled. The SSI rates in the DACC and SSD groups were 1.8% and 5.2%, respectively (p = 0.04). The total cost of SSI prophylaxis and treatment was greater in the control group as compared with the study ...Continue Reading

References

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Citations

May 31, 2018·Current Opinion in Infectious Diseases·Geeta SoodJeanne S Sheffield
Feb 19, 2020·Journal of Wound Care·Jan StryjaDeborah Xuereb
Dec 21, 2016·The Cochrane Database of Systematic Reviews·Jo C DumvilleJane Blazeby
Nov 11, 2020·Journal of Wound Care·Charmaine ChildsJosé Verdú-Soriano
Mar 19, 2021·British Journal of Nursing : BJN·Abdul M SeckamMatthias Augustin

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Methods Mentioned

BETA
esarean
cesarean section

Clinical Trials Mentioned

NCT02168023

Software Mentioned

CONSORT
R

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