Randomized Controlled Trial of E-Counseling for Hypertension: REACH

Circulation. Cardiovascular Quality and Outcomes
Robert P NolanJelena Surikova

Abstract

The efficacy of internet-based interventions to improve hypertension management is not established. We evaluated the therapeutic benefit of e-counseling by adapting best evidence guidelines for behavioral counseling. This multicenter double-blind randomized controlled trial included assessments at baseline, 4 months, and 12 months. Participants were 35 to 74 years of age and diagnosed with hypertension: systolic/diastolic blood pressure (BP) 130 to 180/85 to 110 mm Hg. BP was assessed by automated office measurement. E-Counseling used multimedia and interactive tools to increase motivation and skill for self-care (exercise, diet, medication adherence, and smoking cessation). Control used self-care education. Frequency of contact by our e-platform was equal for both trial arms. Primary end points were change at 4 and 12 months in systolic BP, diastolic BP, pulse pressure, total lipoprotein cholesterol, low-density lipoprotein cholesterol, total lipoprotein cholesterol/high-density lipoprotein cholesterol ratio, non-high-density lipoprotein cholesterol, and Framingham 10-year cardiovascular risk index. Intention-to-treat analysis used generalized linear models adjusted for baseline measures, sex, and medications. Among 264 partic...Continue Reading

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Citations

Jun 18, 2020·World Journal of Clinical Cases·Kannikar WechkunanukulMohammad Hamiduzzaman
Jan 20, 2021·Circulation. Heart Failure·Robert P NolanLisa Marie Mielniczuk
Mar 16, 2021·Journal of Medical Internet Research·Fatimah Najihah Baderol AllamHarrinni Md Noor
May 18, 2021·Journal of Medical Internet Research·Caroline RobertYin-Leng Theng

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