Randomized Evaluation of Cognitive-Behavioral Therapy and Graded Exercise Therapy for Post-Cancer Fatigue

Journal of Pain and Symptom Management
C X SandlerA R Lloyd

Abstract

Cancer-related fatigue is prevalent and disabling. When persistent and unexplained, it is termed post-cancer fatigue (PCF). Cognitive behavioral therapy (CBT) and graded exercise therapy (GET) may improve symptoms and functional outcomes. To evaluate the outcomes of a randomized controlled trial, which assigned patients with post-cancer fatigue to education, or 12 weeks of integrated cognitive-behavioral therapy (CBT) and graded exercise therapy (GET). Three months after treatment for breast or colon cancer, eligible patients had clinically significant fatigue, no comorbid medical or psychiatric conditions that explained the fatigue, and no evidence of recurrence. The CBT/GET arm included individually tailored consultations at approximately two weekly intervals. The education arm included a single visit with clinicians describing the principles of CBT/GET and a booklet. The primary outcome was clinically significant improvement in self-reported fatigue (Somatic and Psychological HEalth REport 0-12), designated a priori as greater than one SD of improvement in fatigue score. The secondary outcome was associated improvement in function (role limitation due to physical health problems-36-Item Short Form Health Survey 0-100) compar...Continue Reading

Citations

Sep 8, 2017·Muscle & Nerve·Claire E FeatherPatsie Polly
Sep 19, 2018·Drug Discoveries & Therapeutics·Patrícia Lopes-SouzaMario Bernardo-Filho
Nov 20, 2018·Disability and Rehabilitation·Ulric S AbonieFlorentina J Hettinga
Sep 26, 2020·Journal of Gerontological Nursing·Jean CodyChristopher R Martell
Apr 29, 2019·The International Journal of Behavioral Nutrition and Physical Activity·Chloe GrimmettClaire Foster
Feb 6, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Patricia SheehanMichael Harrison
Dec 1, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Briana K CliffordDavid Goldstein
Aug 4, 2018·Current Opinion in Supportive and Palliative Care·Nicholas J Hulbert-WilliamsHaryana M Dhillon
Dec 1, 2018·Disability and Rehabilitation·Hilde Tinderholt MyrhaugJan Egil Nordvik
Oct 6, 2020·Seminars in Oncology Nursing·Carolina X SandlerRosalind R Spence
Feb 28, 2020·Journal of Pain and Symptom Management·Rosie TwomeyS Nicole Culos-Reed
Jul 29, 2021·OTJR : Occupation, Participation and Health·Jodie Schroder, Lynette Mackenzie

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