PMID: 7541051Jan 1, 1995Paper

Randomized study of chemoembolization as an adjuvant therapy for primary liver carcinoma after hepatectomy

Journal of Cancer Research and Clinical Oncology
J Q LiG H Li

Abstract

From April 1990 to December 1993, 140 patients were recruited to a randomized study to evaluate transcatheter hepatic arterial chemoembolization (TACE) as an adjuvant therapy for primary liver carcinoma after hepatectomy. This study investigated the principle, techniques and results of TACE. The results showed that the intrahepatic recurrence rate was 48.9% in the patients who underwent radical resection only, but only 21.3% in the patients who also underwent TACE 3-4 weeks after hepatectomy (P < 0.01). The 1-, 2-, 3-, and 4-year survival rates were 72.3%, 52.7%, 35.1%, and 35.1% respectively for the patients who underwent radical resection only, and were 97.9%, 85.5%, 69.5%, and 56.9% for the patients who also underwent TACE 3-4 weeks after radical resection (P < 0.001). The 1-, 2-, 3-, and 4-year survival rates were 38.9%, 0%, 0%, and 0% for the patients who underwent palliative resection only, and were 68.3%, 32.3%, 21.5%, and 21.5% respectively for the patients undergoing TACE 3-4 weeks after palliative hepatectomy (P < 0.001).

Associated Clinical Trials

Citations

Feb 5, 2009·Nature Clinical Practice. Gastroenterology & Hepatology·Giuseppe CabibboAntonio Craxì
Mar 1, 2006·Seminars in Interventional Radiology·J Alexander PalestyJohn F Gibbs
Oct 24, 2002·Journal of Clinical Gastroenterology·S Nahum Goldberg, Muneeb Ahmed
Apr 23, 2014·Journal of Cancer Research and Clinical Oncology·Xiang ChengQi-Chang Zheng
Feb 5, 2013·Journal of Cancer Research and Clinical Oncology·Xiaohong ChenJian Zhou
Jun 18, 2004·Cancer Investigation·David A Kooby, William R Jarnagin
Jan 28, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J-H ZhongG-B Wu
May 21, 2003·Alimentary Pharmacology & Therapeutics·P MathurinS Naveau
Oct 5, 2010·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Jian-Hong Zhong, Le-Qun Li
Mar 31, 2009·Journal of Hepatology·Alejandro Forner, Sasan Roayaie
Apr 11, 2014·Scandinavian Journal of Gastroenterology·Jian-Hong ZhongLe-Qun Li
Oct 28, 2019·Expert Review of Gastroenterology & Hepatology·Shi-Dong LuJian-Hong Zhong
Mar 18, 2011·The Cochrane Database of Systematic Reviews·Roberto S OliveriChristian Gluud
Mar 24, 2021·Frontiers of Medicine·Wei ZhangXiao-Ping Chen
Jan 26, 2020·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Wen ChenTingbo Liang

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