Range of variations in motor unit potentials during reinnervation after traumatic nerve lesions in humans

Annals of Neurology
S Borenstein, J E Desmedt

Abstract

Successive stages in the reinnervation of denervated muscle fibers following a complete or partial motor nerve lesion in humans were analyzed with the concentric needle electrode during voluntary contraction. Motor unit potential (MUP) patterns were displayed by coherent EMG, in which the potential triggers an oscilloscope sweep and a digital delay line enables the early part of the MUP to be displayed. After a complete nerve lesion, MUPs showing the response of as few as one to three muscle fibers can be observed. MUPs become highly polyphasic as more muscle fibers are incorporated. Marked latency jitter and intermittent blocking of components as well as the occurrence of linked potentials result in complex patterns that may be confused with a "myopathic" pattern of brief small spikes if conventional observation of free-running sweeps is used alone. After a partial nerve lesion, the healthy motor axons achieve extensive collateral reinnervation of the denervated muscle fibers whereby linked potentials of various latencies are added after the original MUP. Adequate understanding of these characteristic features can help clarify some current issues in electromyography. The mechanisms by which long-latency linked potentials and d...Continue Reading

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Citations

Sep 9, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Z C Lateva, K C McGill
Feb 19, 2016·Journal of Magnetic Resonance Imaging : JMRI·Alain R ViddeleerMatthijs Oudkerk
Sep 12, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Christian KrarupSimon Archibald
Apr 18, 2015·Acta Neurologica Scandinavica·W N LöscherJ Finsterer
Oct 1, 1986·Journal of Child Neurology·C K Jablecki
Feb 3, 2004·Muscle & Nerve·James M Gilchrist, George M Sachs
Oct 1, 1987·Muscle & Nerve·R G Miller
May 1, 1997·Muscle & Nerve·J Finsterer, B Mamoli

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