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Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering

American Journal of Human Genetics

Nov 1, 2007

Sharon R. Browning, Brian L. Browning

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Abstract

Whole-genome association studies present many new statistical and computational challenges due to the large quantity of data obtained. One of these challenges is haplotype inference; methods for haplotype inference designed for small data sets from candidate-gene studies do not scale we...read more

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    • References23
    • Citations778
    • References23
    • Citations778
  • Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering

    American Journal of Human Genetics

    Nov 1, 2007

    Sharon R. Browning, Brian L. Browning

    PMID: 17924348

    DOI: 10.1086/521987

    Abstract

    Whole-genome association studies present many new statistical and computational challenges due to the large quantity of data obtained. One of these challenges is haplotype inference; methods for haplotype inference designed for small data sets from candidate-gene studies do not scale we...read more

    1010
    2

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    • Citations778
    • References23
    • Citations778
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