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Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering

American Journal of Human Genetics

Oct 10, 2007

Sharon R Browning, Brian L Browning

Abstract

Whole-genome association studies present many new statistical and computational challenges due to the large quantity of data obtained. One of these challenges is haplotype inference; methods for haplotype inference designed for small data sets from candidate-gene studies do not scale we...read more

Mentioned in this Paper

Chromosomes, Human, Pair 1
Recombination, Genetic
Transcription Initiation
Beagle
Genetic Markers
X Chromosome
Chromosomes
Genome Scan
Directed Acyclic Graph
Alleles
1062
2
Paper Details
References
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  • Citations930
123
  • References23
  • Citations930
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Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering

American Journal of Human Genetics

Oct 10, 2007

Sharon R Browning, Brian L Browning

PMID: 17924348

DOI: 10.1086/521987

Abstract

Whole-genome association studies present many new statistical and computational challenges due to the large quantity of data obtained. One of these challenges is haplotype inference; methods for haplotype inference designed for small data sets from candidate-gene studies do not scale we...read more

Mentioned in this Paper

Chromosomes, Human, Pair 1
Recombination, Genetic
Transcription Initiation
Beagle
Genetic Markers
X Chromosome
Chromosomes
Genome Scan
Directed Acyclic Graph
Alleles
1062
2

Similar Papers Found In These Feeds

Structural Biology: Biophysics

Structural Biology: Biophysics describes the study of structural biology using various biophysical techiniques such as imaging, computational modeling, etc. Discover the latest research on structrual biology here.

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Paper Details
References
  • References23
  • Citations930
123
  • References23
  • Citations930
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