Rapid Assessment of Acute Ischemic Stroke by Computed Tomography Using Deep Convolutional Neural Networks.

Journal of Digital Imaging
Chung-Ming LoDaw-Tung Lin

Abstract

Acute stroke is one of the leading causes of disability and death worldwide. Regarding clinical diagnoses, a rapid and accurate procedure is necessary for patients suffering from acute stroke. This study proposes an automatic identification scheme for acute ischemic stroke using deep convolutional neural networks (DCNNs) based on non-contrast computed tomographic (NCCT) images. Our image database for the classification model was composed of 1254 grayscale NCCT images from 96 patients (573 images) with acute ischemic stroke and 121 normal controls (681 images). According to the consensus of critical stroke findings by two neuroradiologists, a gold standard was established and used to train the proposed DCNN using machine-generated image features. Including the earliest DCNN, AlexNet, the popular Inception-v3, and ResNet-101 were proposed. To train the limited data size, transfer learning with ImageNet parameters was also used. The established models were evaluated by tenfold cross-validation and tested on an independent dataset containing 50 patients with acute ischemic stroke (108 images) and 58 normal controls (117 images) from another institution. AlexNet without pretrained parameters achieved an accuracy of 97.12%, a sensiti...Continue Reading

References

Jan 21, 2006·Stroke; a Journal of Cerebral Circulation·Seok Woo YongWen Yu Li
Aug 18, 2006·Lancet Neurology·Keith W MuirJean-Claude Baron
Apr 10, 2009·AJNR. American Journal of Neuroradiology·P G Kranz, J D Eastwood
Nov 17, 2009·Stroke; a Journal of Cerebral Circulation·George M SavvaUNKNOWN Alzheimer's Society Vascular Dementia Systematic Review Group
Sep 15, 2012·International Journal of Stroke : Official Journal of the International Stroke Society·Simerpreet BalAndrew M Demchuk
Jan 30, 2015·Journal of Neurology, Neurosurgery, and Psychiatry·Shenqiang YanMin Lou
Mar 4, 2015·Journal of Medical Systems·Erdal Taşcı, Aybars Uğur
Nov 14, 2015·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·K D KurzM W Kurz
Apr 22, 2016·Cerebrovascular Diseases Extra·Luís Henrique de Castro-AfonsoDaniel Giansante Abud
Oct 28, 2016·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Ryszard S GomolkaWieslaw L Nowinski
Nov 30, 2016·Journal of Digital Imaging·Phillip M Cheng, Harshawn S Malhi
Nov 30, 2016·JAMA : the Journal of the American Medical Association·Varun GulshanDale R Webster
Feb 6, 2017·Circulation Research·Valery L FeiginGeorge A Mensah
Mar 10, 2017·Topics in Magnetic Resonance Imaging : TMRI·Supada Prakkamakul, Albert J Yoo
May 26, 2017·Neuroradiology·Rüdiger von Kummer, Imanuel Dzialowski
Aug 28, 2017·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Daniel M HeifermanWilliam W Ashley
Feb 13, 2018·The Journal of Investigative Dermatology·Seung Seog HanSung Eun Chang
Jul 3, 2019·Computer Methods and Programs in Biomedicine·Gaobo Liang, Lixin Zheng

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