Rapid Detection of the Antibiotic Sulfamethazine in Pig Body Fluids by Paper Spray Mass Spectrometry

Journal of Agricultural and Food Chemistry
Surased SuraritdechachaiThanit Praneenararat

Abstract

We report herein a practical method for nonlethal detection of the antibiotic sulfamethazine in pig body fluids via the combination of simple extraction and paper spray mass spectrometry (PS-MS). This method requires minimal sample preparation while still providing high sensitivities and accuracies in complex matrices including pig whole blood (LOD = 7.9 μg/L; recovery = 95.4-103.7%), pig serum (LOD = 11.5 μg/L; recovery = 103.2-106.2%), and synthetic urine (LOD = 11.2 μg/L; recovery = 99.1-103.2%). Given a known correlation between the level of sulfamethazine in body fluids and edible tissues, this method shows great promise as a practical and nonlethal solution for rapid testing of the drug, which can substantially aid managerial decision in the livestock industry.

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Citations

Feb 18, 2020·Rapid Communications in Mass Spectrometry : RCM·Mengjie Dai, Guangming Huang
Jul 3, 2020·Scientific Reports·Fred P M JjunjuAbraham K Badu-Tawiah
Aug 11, 2021·Scientific Reports·Preeyarad CharoensumranThanit Praneenararat
Oct 8, 2021·Analytical Chemistry·Lucas J SzalwinskiGert Ij Salentijn
Dec 24, 2021·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Weilin L ShelverDavid J Smith

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