Rapid diagnosis of bacteremia.

Applied Microbiology
S M FinegoldW R Winn

Abstract

Early appropriate treatment of bacteremia is important in minimizing morbidity and mortality. Standard blood culture methods are not optimal since several days are often required for recovery and identification of organisms which may be present in the blood. The use of a membrane filter technique allows one to grow any organisms present in blood much more rapidly than by broth or pour plate culture. Furthermore, growth is in the form of typical colonies on the surface of solid media, and a series of rapid diagnostic tests may be used to provide speedy identification. Use of membrane filters also facilitates removal by washing of normal antibacterial factors and antimicrobial drugs which may be present in blood. Although the filter technique yielded the most rapid growth, broth culture and whole blood pour plates yielded more positive cultures and use of all three systems was necessary for maximal recovery of organisms in blood cultures. Data on quantitative aspects of bacteremia in the antimicrobial era are also presented. The number of low level bacteremias (10 colonies/ml or less) is surprisingly high. This is particularly true for gram-negative bacilli; antimicrobial therapy at the time of culture undoubtedly influenced thes...Continue Reading

Citations

Apr 1, 1977·Journal of Clinical Microbiology·J L BeebeP D Ellner
Jan 1, 1977·Journal of Clinical Microbiology·R L KaganJ D MacLowry
Sep 1, 1977·Journal of Clinical Microbiology·C N Shih, E Balish
Aug 1, 1992·Journal of Clinical Microbiology·R J CourcolG R Martin
Nov 1, 1979·Journal of Clinical Microbiology·O V Martinez, T I Malinin
Sep 1, 1984·Journal of Clinical Microbiology·H EtemadiP Vahedifar
Jul 1, 1982·Journal of Clinical Microbiology·M B HerlichJ L Le Frock
Mar 1, 1979·Journal of Clinical Microbiology·G L DornG E Wilson
Jan 1, 1979·Journal of Clinical Microbiology·D G Beckwith
Jul 1, 1986·Journal of Clinical Microbiology·R J CourcolG R Martin
Mar 1, 1982·Infection and Immunity·S M MeyersM L Vasil
Mar 1, 1975·Journal of Clinical Microbiology·W A Thiemke, K Wicher
Jan 1, 1975·Journal of Clinical Microbiology·N M SullivanS M Finegold
Jan 1, 1975·Journal of Clinical Microbiology·N M SullivanS M Finegold
Jan 1, 1978·Journal of Clinical Microbiology·J I MangelsK L Vosti
Jul 1, 1971·Applied Microbiology·J A Washington, P K Yu
May 1, 1983·Journal of Clinical Microbiology·R E LambergJ L LeFrock
May 1, 1983·Journal of Clinical Microbiology·N K HenryJ A Washington
Mar 1, 1976·Journal of Clinical Microbiology·G L DornG G Burson
Mar 1, 1976·Journal of Clinical Microbiology·G L DornJ R Haynes
Mar 1, 1972·Applied Microbiology·S G Farmer, R A Komorowski

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.