Apr 27, 2013

Rapid evolution of a few members of nasuta-albomicans complex of Drosophila: study on two candidate genes, Sod1 and Rpd3

Journal of Molecular Evolution
Mysore S Ranjini, Nallur B Ramachandra

Abstract

Drosophila nasuta nasuta (2n = 8) and D. n. albomicans (2n = 6) are morphologically identical, cross fertile and karyotypically dissimilar pair of chromosomal races belonging to nasuta subgroup of immigrans group of Drosophila. Interracial hybridization between these two races yielded karyotypically stabilized newly evolved Cytoraces with new combinations of chromosomes and DNA content, and are called nasuta-albomicans complex of Drosophila. Along with many other features, striking plasticity in the lifespan has been observed in the karyotypically stabilized members of nasuta-albomicans complex of Drosophila. These findings provide a strong background to understand any changes at the molecular levels. In view of this, we cloned and characterized Sod1 and Rpd3 in the members of nasuta-albomicans complex of Drosophila. The evolution of Sod1 and Rpd3 in D. n. nasuta and D. n. albomicans is contrasting with the other species of Drosophila, at the level of synonymous mutations, intron variation, InDels and secondary structure changes in protein. In the members of NAC of Drosophila there were synonymous changes, variations in intron sequences of Sod1, whereas, in Rpd3, synonymous, nonsynonymous, intron variation, and secondary struct...Continue Reading

  • References22
  • Citations1

References

  • References22
  • Citations1

Citations

Mentioned in this Paper

Fertility
HDAC2 gene
superoxide dismutase 1
Immigrans group
HDAC2 wt Allele
Nucleic Acid Hybridization Procedure
HDAC3 gene
Drosophila melanogaster Proteins
SOD1 protein, human
Hybridization, Intraspecies

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