Rapid high-resolution T1 mapping using a highly accelerated radial steady-state free-precession technique

Journal of Magnetic Resonance Imaging : JMRI
Zhitao LiMaria I Altbach

Abstract

T1 mapping is often used in some clinical protocols. Existing techniques are limited in slice coverage, and/or spatial-temporal resolution, or require long acquisitions. Here we present a multi-slice inversion-recovery (IR) radial steady-state free precession (radSSFP) pulse sequence combined with a principal component (PC) based reconstruction that overcomes these limitations. To develop a fast technique for multi-slice high-resolution T1 mapping. Technical efficacy study done prospectively. IR-radSSFP was tested in phantoms, five healthy volunteers, and four patients with abdominal lesions. IR-radSSFP was implemented at 3T. Computer simulations were performed to optimize the flip angle for T1 estimation; testing was done in phantoms using as reference an IR spin-echo pulse sequence. T1 mapping with IR-radSSFP was also assessed in vivo (brain and abdomen) and T1 values were compared with literature. T1 maps were also compared with a radial IR-FLASH technique. A two-tailed t-test was used to compare T1 values in phantoms. A repeatability study was carried out in vivo using Bland-Altman analysis. Simulations and phantom experiments showed that a flip angle of 20˚ was optimal for T1 mapping. When comparing single to multi-slice e...Continue Reading

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Citations

Feb 19, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Carole LazarusPhilippe Ciuciu
Sep 17, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Xiaoqing WangMartin Uecker
Feb 14, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Li FengYang Yang
Jan 1, 2022·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Zhitao LiLi Feng

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