Rapid immunoblot method for diagnosis of acute Mycoplasma pneumoniae infection

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
N CimolaiP J Middleton

Abstract

A rapid immunoblotting technique based on the IgM response to a major immunogenic protein is described for the diagnosis of Mycoplasma pneumoniae infection. Using results of the complement fixation test as the criterion for diagnosis, the rapid immunoblot method was positive in 95.7% of patients. The sensitivity was reduced to 81.9% if the test was performed on either single sera or acute sera only from serum pairs. Although the few sera that failed to demonstrate a positive IgM response were more likely to be from older patients, there was a consistent IgM response recorded for both younger (less than 20 years) and older (greater than or equal to 20 years) patients.

References

Apr 1, 1988·Diagnostic Microbiology and Infectious Disease·N CimolaiD E Woods
Jan 1, 1988·Scandinavian Journal of Infectious Diseases·T VikerforsC A Pettersson
Jun 1, 1988·Diagnostic Microbiology and Infectious Disease·R C TiltonR W Ryan
Nov 1, 1988·Journal of Clinical Microbiology·J B BasemanD L Rose
Apr 1, 1984·European Journal of Clinical Microbiology·A J van GriethuysenA M van Loon

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Citations

Jul 1, 1995·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D LiebermanA Porath
Feb 26, 2008·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Nevio Cimolai
Aug 30, 2008·FEMS Microbiology Reviews·Thomas Prescott AtkinsonKen B Waites

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