Rapid impact of rotavirus vaccine introduction to the National Immunization plan in southern Israel: comparison between 2 distinct populations

Vaccine
Noga Givon-LaviR Dagan

Abstract

Rotavirus vaccines were licensed in Israel in 2007, and in 2011 the pentavalent-vaccine (RV5) was introduced into the Israeli National Immunization plan. To determine the effect of rotavirus-vaccines on the incidence of hospital visits due to rotavirus gastroenteritis (RVGE) and all-cause diarrhea in Jewish and Bedouin children <5 year residing in southern Israel. We conducted a population-based, prospective, observational study. Data from 2006 through 2013 were analyzed. Our hospital is the only medical center in the region, enabling age-specific incidences calculation. In the pre-vaccine period, the overall RVGE hospital visits rates per 1000 in children <12, 12-23 and 24-59 m were 16.1, 18.6 and 1.4 in Jewish children, respectively. The respective rates in Bedouin children were 26.4, 12.5 and 0.7 (P<0.001 for <12 m). Hospitalization rates were higher among Bedouin than among Jewish children (60.0% vs. 39.7%, P<0.001). Vaccine uptake was faster in the Jewish vs. the Bedouin population. In the year following RV5 introduction, RVGE hospital visits rates declined by 82%, 70% (P<0.001 both) and 36% (P=0.092) in Jewish children <12, 12-23 and 24-59 m, respectively. In Bedouin children, the respective RVGE rates declined by 70% (P<...Continue Reading

References

Jan 6, 2006·The New England Journal of Medicine·Guillermo M Ruiz-PalaciosUNKNOWN Human Rotavirus Vaccine Study Group
Jan 6, 2006·The New England Journal of Medicine·Timo VesikariUNKNOWN Rotavirus Efficacy and Safety Trial (REST) Study Team
Feb 24, 2006·Emerging Infectious Diseases·Umesh D ParasharRoger I Glass
Mar 28, 2007·The Journal of Infectious Diseases·Pierre Van DammeUNKNOWN REVEAL Study Group
Jun 28, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Daniel C PayneUNKNOWN New Vaccine Surveillance Network (NVSN)
Sep 1, 2011·The Journal of Infectious Diseases·Ben A LopmanUmesh D Parashar
Sep 4, 2012·Vaccine·S Ben-ShimolUNKNOWN Israeli Bacteremia and Meningitis Active Surveillance Group
Apr 8, 2014·Expert Review of Vaccines·Rolando Ulloa-Gutierrez, María L Avila-Aguero
Apr 25, 2014·The Lancet Infectious Diseases·N ParezT Vesikari
Jul 23, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jacqueline E Tate, Umesh D Parashar

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Citations

Apr 10, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Eyal LeshemRon Dagan
Mar 11, 2017·Human Vaccines & Immunotherapeutics·Khitam Muhsen, Daniel Cohen
Dec 7, 2017·Human Vaccines & Immunotherapeutics·Marieke L A de HoogPatricia Bruijning-Verhagen
Jun 10, 2018·Acta Paediatrica·Sharon DanielBaruch Yerushalmi
Aug 16, 2016·Canadian Journal of Public Health = Revue Canadienne De Santé Publique·Virginie GosselinMélissa Généreux
Jan 28, 2021·Israel Journal of Health Policy Research·Chen Stein-Zamir, Shmuel Rishpon
Jan 29, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ron DaganNoga Givon-Lavi

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