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Rapid Intestinal Uptake and Targeted Delivery to the Liver Endothelium Using Orally Administered Silver Sulfide Quantum Dots

ACS Nano

Jan 25, 2020

Nicholas J HuntVictoria C Cogger

Abstract

Quantum dots (QDs) are used for imaging and transport of therapeutics. Here we demonstrate rapid absorption across the small intestine and targeted delivery of QDs with bound materials to the liver sinusoidal endothelial cells (LSECs) or hepatocytes in vitro and in vivo following oral a...read more

Mentioned in this Paper

Gelatin
Lysosomes
Endothelium
Micropinocytosis
ALB
Fluorescent stain
Caveolin-mediated Endocytosis
Administration Procedure
Silver sulfide
Intestines
5
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Rapid Intestinal Uptake and Targeted Delivery to the Liver Endothelium Using Orally Administered Silver Sulfide Quantum Dots

ACS Nano

Jan 25, 2020

Nicholas J HuntVictoria C Cogger

PMID: 31976646

DOI: 10.1021/acsnano.9b06071

Abstract

Quantum dots (QDs) are used for imaging and transport of therapeutics. Here we demonstrate rapid absorption across the small intestine and targeted delivery of QDs with bound materials to the liver sinusoidal endothelial cells (LSECs) or hepatocytes in vitro and in vivo following oral a...read more

Mentioned in this Paper

Gelatin
Lysosomes
Endothelium
Micropinocytosis
ALB
Fluorescent stain
Caveolin-mediated Endocytosis
Administration Procedure
Silver sulfide
Intestines
5

Similar Papers Found In These Feeds

Type 2 Diabetes

This feed focuses on Type 2 Diabetes, a disease where the body doesn’t produce or respond to insulin anymore, leading to abnormal glucose levels in the blood.

Exocytosis & Endocytosis: Imaging

Dynamin GTPases are proteins that are responsible for endocytosis in cells, as well as division of organelles, cytokinesis, and pathogen resistance. Discover the latest research on dynamin GTPases here.

Related Papers

American Journal of Physiology. Gastrointestinal and Liver Physiology

Role of liver sinusoidal endothelial cells and stabilins in elimination of oxidized low-density lipoproteins

American Journal of Physiology. Gastrointestinal and Liver PhysiologyOctober 30, 2010
Ruomei LiDmitri Svistounov
Comparative Hepatology

Scavenger properties of cultivated pig liver endothelial cells

Comparative HepatologyAugust 13, 2004
Kjetil H ElvevoldBård Smedsrød
Paper Details
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