Rapid palliative radiotherapy unit: multidisciplinary management of bone metastases.

La Radiologia medica
V DonatoA Morrone

Abstract

The aim of this study was to highlight the advantages of rapid access to a palliative radiotherapy unit adopting a multidisciplinary approach to symptom management to relieve pain and improve quality of life in patients with bone metastases. From January 2007 to December 2008, 142 oncological patients were treated with linear accelerator radiotherapy (RT) administered in a single 8-Gy fraction. The European Organization for Research and Treatment Quality of Life Questionnaire (EORTC QLQ-C30) was administered to each patient at admission and at subsequent intervals. A traditional simulator was used to define the correct patient setup, and all treatment plans were performed with a two-dimensional technique.. Ninety-six patients agreed to fill in the EORTC QLQ-C30 questionnaire; 80 actually completed it. Twelve weeks after RT, a reduction in pain level compared with baseline (T0) was recorded, which was classified as 1 in 36 patients (45%) and 2 in 44 patients (55%). Pain interference with daily activities was also recorded, with significantly reduced scores with respect to T0: 1 in eight patients (10%), 2 in 28 patients (35%) and 3 in 44 patients (55%); quality of life scores also improved with respect to T0: 2 in 28 patients (35...Continue Reading

References

Sep 7, 2000·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·E ChowR Connolly
Jan 3, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J HuangW J Mackillop
Mar 14, 2003·Critical Reviews in Oncology/hematology·Vittorio DonatoAlfredo Zurlo
May 18, 2004·International Journal of Radiation Oncology, Biology, Physics·Yvette M van der LindenUNKNOWN Dutch Bone Metastasis Study Group
Mar 2, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ernesto MaranzanoPaolo Latini
Apr 28, 2005·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·C DanjouxM Farhadian
Apr 30, 2005·Journal of Palliative Medicine·P Kirkbride, R Barton
Jun 2, 2005·Journal of the National Cancer Institute·William F HartsellMichelle DeSilvio
Mar 21, 2006·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Yvette M van der LindenUNKNOWN Dutch Bone Metastasis Study Group
Jun 24, 2006·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Stein KaasaOivind Bruland
Sep 15, 2006·Clinical Oncology : a Journal of the Royal College of Radiologists·J S Y WuN Hagen
Nov 10, 2006·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·D Andrew LoblawPadraig Warde
Nov 10, 2006·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Nicole M E BradleyEdward Chow
Jun 17, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Palmira Foro ArnalotManuel Algara López
Jun 21, 2008·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·A FairchildD Severin
Sep 16, 2008·Journal of Pain and Symptom Management·Stephanie L JarosekRoger Feldman

❮ Previous
Next ❯

Citations

Feb 12, 2013·Journal of Pain & Palliative Care Pharmacotherapy·Beilei CaiDavid K Gaffney
Jul 9, 2014·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Shilo LefresneRobert Olson
May 4, 2020·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·E OldenburgerK Haustermans
Aug 23, 2020·Clinical Oncology : a Journal of the Royal College of Radiologists·K DennisA Rembielak

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.