Rapid prediction of inducible clarithromycin resistance in Mycobacterium abscessus

Molecular and Cellular Probes
Yan Chun ZhuKimberlee A Musser

Abstract

We have developed a single tube TaqMan(®) real-time PCR assay that differentiates the full-length and truncated erm(41) gene to predict inducible resistance to clarithromycin in Mycobacterium abscessus. A study of 87 clinical isolates found this assay to be 90.8% concordant to conventional drug susceptibility testing results for the prediction of inducible clarithromycin drug resistance.

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Citations

Nov 7, 2018·Antimicrobial Agents and Chemotherapy·Samuel LipworthTimothy Walker
May 14, 2021·Frontiers in Cellular and Infection Microbiology·Laura VictoriaJaime Robledo

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