Rapid quantification of aloin A and B in aloe plants and aloe-containing beverages, and pharmaceutical preparations by microchip capillary electrophoresis with laser induced fluorescence detection

Journal of Separation Science
Meng-Wei XiaoXun Liao

Abstract

A microchip capillary electrophoresis coupled with laser induced fluorescence detection method for the fast determination of aloin was developed and comprehensively applied for the quantification of aloin A and B present in seven aloe plant species, 42 aloin-containing crude drugs, ten aloe pharmaceutical preparations, and four aloe gel-containing functional foods. The excitation and emission wavelengths for detection of both aloins were set at 473 and 520 nm, respectively. Sample analysis on a 35 mm length of glass microchip channel was completed within 40 s. An interference study indicated that the other main anthraquinones present in the samples did not interrupt with the target aloins detection, demonstrating the good selectivity of this method. It is demonstrated that this method is fast, facile, and specific for determination of aloin A and B from matrix samples which can be applied to the quality control of a wide varieties of aloe species and aloe-derived products.

References

Aug 1, 1970·Planta medica·R K Mapp, T J McCarthy
Mar 20, 2001·Journal of Chromatography. B, Biomedical Sciences and Applications·H KuzuyaT Chihara
Oct 16, 2001·Journal of Agricultural and Food Chemistry·D SaccùG Procida
Nov 13, 2003·Electrophoresis·Detlev Belder, Martin Ludwig
May 1, 2004·Critical Reviews in Food Science and Nutrition·Kojo Eshun, Qian He
Nov 9, 2004·International Immunopharmacology·Mahmoud A ElSohlyTimothy P Murphy
May 13, 2006·Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews·Mary D Boudreau, Frederick A Beland
Mar 20, 2010·Critical Reviews in Food Science and Nutrition·Elena Rodríguez RodríguezCarlos Díaz Romero
Sep 2, 2010·Journal of Separation Science·Salvatore FanaliMaria Augusta Raggi
Oct 12, 2010·Journal of Pharmaceutical and Biomedical Analysis·Silvia A CoranMassimo Bambagiotti-Alberti
Nov 26, 2010·Analytical and Bioanalytical Chemistry·Adriana RizzoDaniel P Kirby
Feb 24, 2011·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Yong HuangHong Liang
Jun 8, 2011·Talanta·Bingrong HuangJin Ouyang
May 24, 2014·Electrophoresis·Pavel RezankaDavid Sýkora
Apr 10, 2015·Analytical and Bioanalytical Chemistry·Jayson V PagaduanAdam T Woolley
Oct 27, 2015·Journal of Separation Science·Sille Štěpánová, Václav Kašička
Aug 6, 2016·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Yan ZhaoJong Seong Kang
Nov 3, 2016·Journal of Separation Science·Sille Štěpánová, Václav Kašička

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Citations

May 26, 2020·Critical Reviews in Analytical Chemistry·Marwa A A Ragab, Eman I El-Kimary
Jan 7, 2021·Journal of Pharmaceutical and Biomedical Analysis·Gereziher SibhatErwin Adams
Jul 25, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Marcin GackowskiArtur Bogacz

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