Rapid response team-triggered procalcitonin measurement predicts infectious intensive care unit transfers*

Critical Care Medicine
Richard G WunderinkKurt D Reed

Abstract

Determine if procalcitonin at the time of initial rapid response team activation identifies patients who are likely to need subsequent intensive care unit transfer. Prospective observational cohort study. Urban, tertiary care hospital with rapid response team activation through an electronic modified early warning score. One hundred nineteen oncology and 100 consecutive non-oncology patients after initial rapid response team visit precipitated by an elevated electronic modified early warning score were recruited. Rapid response team activations by request of nursing or for other reasons were not studied. Five oncology patients seen by a rapid response team for complications of interleukin-2 therapeutic infusions were subsequently excluded. Residual serum from the next ordered clinical test (within 12 hrs) was retrieved, frozen, and stored for procalcitonin determination. A second sample 12-24 hrs after the initial specimen was also retrieved if available and if the patient had not yet been transferred to the intensive care unit. Seventy-three patients (33%) were transferred to the intensive care unit. Rapid response team activations that did not result in intensive care unit transfer had significantly lower procalcitonin levels...Continue Reading

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Citations

Oct 13, 2012·Medicina intensiva·A Abella ÁlvarezF Gordo Vidal
May 17, 2019·BMC Medical Informatics and Decision Making·James MalychaPeter J Watkinson

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