Rapid three-dimensional functional magnetic resonance imaging of the initial negative BOLD response

Journal of Magnetic Resonance
Martin A LindquistLawrence Shepp

Abstract

Functional MRI is most commonly used to study the local changes in blood flow that accompanies neuronal activity. In this work we introduce a new approach towards acquiring and analyzing fMRI data that instead provides the potential to study the initial oxygen consumption in the brain that accompanies activation. As the oxygen consumption is closer in timing to the underlying neuronal activity than the subsequent blood flow, this approach promises to provide more precise information about the location and timing of activity. Our approach is based on using a new single shot 3D echo-volumar imaging sequence which samples a small central region of 3D k-space every 100ms, thereby giving a low spatial resolution snapshot of the brain with extremely high temporal resolution. Explicit and simple rules for implementing the trajectory are provided, together with a straightforward reconstruction algorithm. Using our approach allows us to effectively study the behavior of the brain in the time immediately following activation through the initial negative BOLD response, and we discuss new techniques for detecting the presence of the negative response across the brain. The feasibility and efficiency of the approach is confirmed using data f...Continue Reading

References

Nov 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Z H ChoT H Lim
Jul 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·S OgawaK Ugurbil
May 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P Irarrazabal, D G Nishimura
Mar 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R S MenonK Uğurbil
Aug 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G P ZientaraF A Jolesz
Jul 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·T Ernst, J Hennig
Jul 1, 1993·Journal of Magnetic Resonance Imaging : JMRI·J J van VaalsJ A den Boer
Feb 1, 1993·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S OgawaB Barrere
Nov 1, 1995·Journal of Computer Assisted Tomography·P MansfieldJ Hykin
Jun 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J H GaoP T Fox
Jan 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P R Harvey, P Mansfield
Apr 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·L P PanychJ Hennig
Mar 1, 1997·Journal of Magnetic Resonance Imaging : JMRI·Y YangJ H Duyn
Apr 1, 1997·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S G KimK Uğurbil
Nov 5, 1997·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·D K Sodickson, W J Manning
Jan 14, 1998·Neuroreport·W RichterS G Kim
Jan 23, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K J FristonR Turner
Sep 2, 1998·Proceedings of the National Academy of Sciences of the United States of America·R S MenonJ S Gati
Jan 29, 2000·Nature Neuroscience·D S KimS G Kim
Apr 19, 2000·Nature Neuroscience·N Logothetis
Aug 5, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·T Q DuongS G Kim
Dec 18, 2001·NMR in Biomedicine·E YacoubX Hu
Mar 22, 2002·NeuroImage·Christopher R GenoveseThomas Nichols
Nov 7, 2002·Journal of Magnetic Resonance·Qing X YangMichael B Smith
Oct 16, 2003·Magnetic Resonance Imaging·Sebastian SabatPablo Irarrazaval
Jul 30, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Roberto MirPablo Irarrazaval
Aug 24, 2004·Nature Neuroscience·Jeffrey K ThompsonRalph D Freeman
Sep 5, 2006·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·Martin A LindquistQing X Yang
Nov 8, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Wietske van der ZwaagRichard Bowtell
Nov 6, 2007·Human Brain Mapping·Martin A Lindquist, Tor D Wager
Jan 1, 1994·IEEE Transactions on Medical Imaging·Z P Liang, P C Lauterbur

❮ Previous
Next ❯

Citations

Nov 26, 2009·Journal of Integrative Neuroscience·Peter A Bandettini
May 23, 2012·Biomedical Engineering Online·Oliver JerominVince D Calhoun
Mar 1, 2011·Brain Research Reviews·Hong PanEmily Stern
Apr 3, 2009·Annals of the New York Academy of Sciences·Peter A Bandettini
Aug 23, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kawin SetsompopLawrence L Wald
May 11, 2010·NeuroImage·Gregory R LeeJean A Tkach
Jun 12, 2013·Journal of Neuroscience Methods·Zhongnan Fang, Jin Hyung Lee
Nov 13, 2018·Frontiers in Neurorobotics·Keum-Shik Hong, Amad Zafar
Sep 9, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Nadine N GraedelKarla L Miller

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cajal Bodies & Gems

Cajal bodies or coiled bodies are dense foci of coilin protein. Gemini of Cajal bodies, or gems, are microscopically similar to Cajal bodies. It is believed that Cajal bodies play important roles in RNA processing while gems assist the Cajal bodies. Find the latest research on Cajal bodies and gems here.

Related Papers

Journal of Magnetic Resonance Imaging : JMRI
Cécile RabraitF Lethimonnier
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Wietske van der ZwaagRichard Bowtell
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Thimo GrotzJürgen Hennig
Proceedings of the National Academy of Sciences of the United States of America
Karla L MillerTimothy E J Behrens
© 2021 Meta ULC. All rights reserved