Rapid viral rebound after 4 years of suppressive therapy in a seronegative HIV-1 infected infant treated from birth

The Pediatric Infectious Disease Journal
Karina M ButlerNigel Klein

Abstract

Attention has focused on the possibility of cure for HIV infected infants if treated promptly after delivery. The "Mississippi baby," who had very prolonged remission after antiretroviral discontinuation, may represent a unique situation. We report an infant treated from birth, who seroreverted, remained virologically suppressed, and had undetectable HIV-1 RNA and DNA at 4 years of age, yet experienced virologic rebound within days of discontinuation of antiretroviral therapy.

References

Jul 9, 2004·HIV Medicine·M SharlandUNKNOWN PENTA Steering Committee
Oct 25, 2013·The New England Journal of Medicine·Deborah PersaudKatherine Luzuriaga

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Citations

Jan 16, 2016·Annual Review of Medicine·Katherine Luzuriaga
Apr 18, 2015·The Journal of Infectious Diseases·Kelly A Metcalf PateJoel N Blankson
Mar 15, 2016·Nature Reviews. Immunology·Philip J GoulderEllen M Leitman
Sep 21, 2016·Expert Review of Anti-infective Therapy·Pierre FrangeStéphane Blanche
Mar 17, 2018·Current Opinion in HIV and AIDS·Thomas Joshua PasvolSarah Fidler
Mar 10, 2015·Journal of Neurovirology·B J BrewB Spencer
Jun 30, 2018·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Elena ChiappiniMaurizio de Martino
Jun 3, 2016·PLoS Pathogens·Mohamed Abdel-MohsenSatish K Pillai
Dec 29, 2015·Current Opinion in Pediatrics·Kaitlin Rainwater-LovettDeborah Persaud
Apr 8, 2016·Current Opinion in HIV and AIDS·Lydie Trautmann
Feb 20, 2020·The Journal of Antimicrobial Chemotherapy·Josephine BriceSidonie Lambert-Niclot
Apr 6, 2017·Frontiers in Immunology·Fabio E LealLishomwa C Ndhlovu
Dec 29, 2015·Current Pediatrics Reports·Maria H KimElaine J Abrams
Feb 26, 2016·Indian Journal of Public Health·Ramalingam Sekar, Manoharan Mythreyee

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