Rapidly growing, multifocal, benign choroid plexus tumor in an infant: case report

Journal of Neurosurgery. Pediatrics
Kalina A MisiolekDaniel H Fulkerson

Abstract

Choroid plexus papillomas (CPPs) are rare, benign tumors that can arise in young children. Most pediatric patients present with signs of hydrocephalus and require immediate treatment. The natural history of choroid plexus tumors in children without hydrocephalus is poorly defined. In this report, the authors present the very rare case of a child without hydrocephalus but with two intraventricular choroid plexus tumors discovered shortly after birth. Initial imaging had been performed for seizures and showed agenesis of the corpus callosum and enhancing tumors in the third and left lateral ventricles. Sequential imaging demonstrated rapid growth of both tumors. The lateral tumor was removed when the child was 3 months of age. A histological examination of the specimen showed benign features with an elevated mitotic rate. Given the patient's age of under 3 years, the diagnosis was WHO grade I CPP. The third ventricle tumor grew rapidly. A second surgery was performed and this tumor was resected. Again, the pathological diagnosis was WHO grade I CPP. The authors present this rare case and discuss the current relevant literature.

References

Jan 1, 1990·Acta neurochirurgica·G LenaM Choux
Mar 1, 1982·Archives of Neurology·H TachibanaT Tamai
Jul 1, 1995·Brain & Development·R R TrifilettiE Parano
Mar 6, 1998·Journal of Neurosurgery·P PencaletD Renier
Jun 26, 1999·Lancet·J E WolffR M Egeler
Dec 22, 2000·Pediatric Neurosurgery·D A Taggard, A H Menezes
Feb 13, 2001·Surgical Neurology·M G Nagib, M T O'Fallon
Feb 4, 2003·Arquivos de neuro-psiquiatria·Geraldo Pianetti FilhoMárcia Cristina da Silva
Mar 18, 2004·Neurosurgery Clinics of North America·Nalin Gupta
Jul 10, 2007·Acta Neuropathologica·David N LouisPaul Kleihues
Jun 18, 2009·British Journal of Neurosurgery·Aimun A B JamjoomMohamed B Satti
Jul 21, 2010·Neurology India·Girish MenonC V Gopalakrishnan
Oct 12, 2010·Acta neurochirurgica·Azize BoströmMatthias Simon
Oct 6, 2011·British Journal of Neurosurgery·Hideki OgiwaraTadanori Tomita
May 1, 2012·Clinical Neuropathology·Martin ScholsemManuel Deprez
Sep 4, 2012·Journal of Neurosurgery. Pediatrics·Chetan BettegowdaEdward S Ahn
Mar 8, 2013·Journal of Neuro-oncology·Michael SafaeeAndrew T Parsa
Mar 15, 2013·The Journal of Neuropsychiatry and Clinical Neurosciences·Rashmi ArasappaGanesan Venkatasubramanian
Jul 16, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Eun Jung KohSeung-Ki Kim
Sep 17, 2013·Pediatric Blood & Cancer·Guss ZacharyTerezakis Stephanie
Oct 30, 2013·Journal of Neuro-oncology·Matthew Z SunAndrew T Parsa
Dec 17, 2014·Pediatric Neurosurgery·Sandi LamAndrew Jea
May 20, 2016·Journal of Pediatric Neurosciences·Sharad PandeyPraveen Kumar Gupta
Jul 4, 2016·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Marwah M AbdulkaderAaron A Cohen-Gadol
Jun 14, 2017·Surgical Neurology International·Avra S LaarakkerRick Abbott
Aug 26, 2017·Journal of Neurosurgery. Pediatrics·Ramin A MorshedLauren R Ostling

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
H AkilJ Singh
Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
T ShutoI Yamamoto
© 2022 Meta ULC. All rights reserved