PMID: 9185223May 1, 1997Paper

Rapidly progressive T cell lymphoma presenting as acute renal failure: case report and review of the literature

Pediatric Pathology & Laboratory Medicine : Journal of the Society for Pediatric Pathology, Affiliated with the International Paediatric Pathology Association
T S NeuhauserJ K Taubenberger

Abstract

We describe a case of peripheral T cell lymphoma that is remarkable for its fulminate course and selective targeting of both kidneys. The patient was a 6-year-old girl who was in her usual state of good health until the onset of abdominal pain and fever. She was treated for acute oliguric renal failure and visual disturbances. A renal biopsy was performed. Biopsy findings were interpreted as suggestive of a vasculitic process, and treatment was initiated for a presumptive diagnosis of Wegener's granulomatosis. The patient died 3 days following admission, and autopsy revealed extensive bilateral kidney infiltration by a peripheral T cell lymphoma. The remainder of the body was spared with the exception of mild infiltration of the pulmonary parenchyma and choroid plexus by neoplastic lymphocytes. The neoplastic nature of the disease was confirmed utilizing immunoperoxidase stains and T cell receptor gene rearrangement. Primary renal lymphoma and renal failure attributable to involvement by lymphoma are rare findings that should be considered when other more common causes of renal insufficiency have been excluded. The presenting clinical complaints are generally of short duration, nonspecific, and atypical. Most patients exhibit o...Continue Reading

Citations

Sep 27, 2006·Clinical and Laboratory Haematology·L AiraghiL Baldini
Mar 5, 2010·Paediatric Anaesthesia·Gregory J Latham, Robert S Greenberg
Mar 18, 2004·American Journal of Preventive Medicine·Stephanie L ScovilleJohn A Kark
Aug 1, 2002·Leukemia & Lymphoma·Oya Levendoglu-TugalRobert Weiss
Apr 12, 2003·Leukemia & Lymphoma·Ioannis D VenizelosVasiliki Garipidou

❮ Previous
Next ❯

Related Concepts

Related Feeds

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Related Papers

The American Journal of Surgical Pathology
B M OsborneJ J Butler
Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Kais HarzallahEzzedine Boussema
Journal of Gastrointestinal Oncology
Jonah CohenSimon C Robson
[Rinshō ketsueki] The Japanese journal of clinical hematology
Jiro TadokoroS Furusawa
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
J P BroulandD Nochy
© 2021 Meta ULC. All rights reserved