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Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma

Oncogene

Jun 16, 2005

Antoine M SnijdersDonna G Albertson

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Abstract

Genomes of solid tumors are characterized by gains and losses of regions, which may contribute to tumorigenesis by altering gene expression. Often the aberrations are extensive, encompassing whole chromosome arms, which makes identification of candidate genes in these regions difficult....read more

Mentioned in this Paper

TLN1 gene
Gene Expression
RBPJ gene
Gene Amplification
Squamous Cell Carcinoma - Category
Brachydactyly
MMP7 gene
LAMA4 gene
Cell Fate Specification
Neoplastic Cell Transformation
48
Paper Details
References
  • References39
  • Citations134
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Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma

Oncogene

Jun 16, 2005

Antoine M SnijdersDonna G Albertson

PMID: 15824737

DOI: 10.1038/sj.onc.1208601

Abstract

Genomes of solid tumors are characterized by gains and losses of regions, which may contribute to tumorigenesis by altering gene expression. Often the aberrations are extensive, encompassing whole chromosome arms, which makes identification of candidate genes in these regions difficult....read more

Mentioned in this Paper

TLN1 gene
Gene Expression
RBPJ gene
Gene Amplification
Squamous Cell Carcinoma - Category
48

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Paper Details
References
  • References39
  • Citations134
12345...

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