Rare and Fatal Gastrointestinal Mucormycosis (Zygomycosis) in a COVID-19 Patient: A Case Report

Clinical Endoscopy
Epifanio Silvino do Monte JuniorEduardo Guimarães Hourneaux de Moura

Abstract

The novel coronavirus disease (COVID-19) quickly spread to all continents. However, data regarding all the signs and symptoms of COVID-19 are insufficient. Patients with COVID-19 might present higher susceptibility to fungal coinfections. Mucormycosis is a rare and often life-threatening fungal disease characterized by vascular invasion by hyphae, resulting in thrombosis and necrosis. This is the first case report of mucormycosis in a COVID-19 patient. An 86-year-old male patient was admitted to the emergency room with acute diarrhea, cough, dyspnea, and fever from 5 days prior. Blood tests revealed a hemoglobin level of 14.3 mg/dL. Five days following the admission, the patient presented with melena and a hemoglobin level of 5.6 mg/dL. A transfusion of three units of red blood cells was required. Esophagogastroduodenoscopy (EGD) revealed two giant gastric ulcers with necrotic debris and a deep hemorrhagic base without active bleeding. Furthermore, biopsies confirmed mucormycosis. Despite intensive care, the patient died 36 hours after the EGD.

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Citations

Mar 7, 2021·Journal of Fungi·Anubhav KanwarBrendan R Jackson
May 4, 2021·Frontiers in Public Health·Sanjana Fatema ChowdhurySaeed Anwar
May 31, 2021·Indian Journal of Medical Microbiology·Hardeva Ram NeharaPramendra Sirohi
Jun 5, 2021·Medical Hypotheses·Deepak PandiarP M Shameena
May 27, 2021·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Carolt AranaNúria Esforzado
Jul 3, 2021·Therapeutic Advances in Infectious Disease·Alfonso J Rodriguez-MoralesAndrés F Henao-Martínez
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Jul 9, 2021·Environmental Research·Iyer MahalaxmiBalachandar Vellingiri
Jul 25, 2021·Infection·Jaffar A Al-TawfiqKuldeep Dhama
Jul 14, 2021·Mycoses·Lav SelarkaJonathan J Y Ong
Aug 7, 2021·Journal of Fungi·María Guadalupe Frías-De-LeónErick Martínez-Herrera
Aug 29, 2021·Travel Medicine and Infectious Disease·Alfonso J Rodriguez-MoralesSebastian Abanto-Urbano
Aug 29, 2021·Travel Medicine and Infectious Disease·Ahmet DilekHakan Leblebicioglu
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Nov 18, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Taha K AlloushHossam M Shokri

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Methods Mentioned

BETA
biopsy

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