PMID: 32668844Jul 17, 2020Paper

Rare Cancers in the Genitourinary Tract

Gan to kagaku ryoho. Cancer & chemotherapy
Yoshiyuki NagumoHiroyuki Nishiyama

Abstract

Many types of rare cancers develop in the genitourinary tract. However, guidelines underlying clinical practice have not been established due to the lack of nationwide epidemiological data for many of these cancers. While epidemiological data in Western countries has been revealed by population-based study, it has been attempted to build the data using hospital-based cancer registry(HBCR)in Japan. The data from nationwide designated cancer care hospitals and other core cancer care hospitals includes the patients' demographics, tumor characteristics, and the first course of treatment. Although HBCR data does not reflect the status of clinical practice at all hospitals, it may be a useful tool for understanding the actual practice of rare cancers in Japan. We focused on the current status and prospects of penile and urachal cancer, which are relatively common in daily clinical practice. A standard of care has not been established for penile and urachal cancer patients, and the prognoses of those patients are poor. Recently, genomic analysis using a next-generation sequencer has been actively performed for many types of cancer. It is an important future task to establish a standard of care for patients with rare cancers based on m...Continue Reading

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