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Rare protein coding variants implicate genes involved in risk of suicide death

bioRxiv

Jan 11, 2020

Emily DiBlasiHilary Coon

Abstract

Suicide death is a worldwide health crisis, claiming close to 800,000 lives per year. Recent evidence suggests that prediction and prevention challenges may be aided by discoveries of genetic risk factors. Here we focus on the role of rare (MAF <1%), putatively functional single nucleot...read more

Mentioned in this Paper

Schizophrenia
Immune System
Electronic Health Records
TNKS1BP1 protein, human
Analysis
Health Care Organization
GPR116
Genome-Wide Association Study
SNAPC1 gene
Gene Mutant
7
Paper Details
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Rare protein coding variants implicate genes involved in risk of suicide death

bioRxiv

Jan 11, 2020

Emily DiBlasiHilary Coon

DOI: 10.1101/2020.01.10.902304

Abstract

Suicide death is a worldwide health crisis, claiming close to 800,000 lives per year. Recent evidence suggests that prediction and prevention challenges may be aided by discoveries of genetic risk factors. Here we focus on the role of rare (MAF <1%), putatively functional single nucleot...read more

Mentioned in this Paper

Schizophrenia
Immune System
Electronic Health Records
TNKS1BP1 protein, human
Analysis
Health Care Organization
GPR116
Genome-Wide Association Study
SNAPC1 gene
Gene Mutant
7

Similar Papers Found In These Feeds

Schizophrenia And Bipolar Disorder: Genome Sequencing

Genome-wide and high-throughput DNA sequencing in Schizophrenia and Bipolar Disorder can be used to identify genes and pathways that contribute to disease risk. Here is the latest research.

Inflammation and Immunity in Schizophrenia

Schizophrenia is a complex mental disease caused by a combination of serial alterations in genetic and environmental factors, including inflammation and immunity. Here is the latest research.

Related Papers

Nature Neuroscience

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Nature NeuroscienceJanuary 20, 2015
Network and Pathway Analysis Subgroup of Psychiatric Genomics Consortium
Paper Details
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