PMID: 11908970Mar 23, 2002Paper

Rare sesquiterpenes from the algicolous fungus Drechslera dematioidea

Journal of Natural Products
C OsterhageAnthony D Wright

Abstract

From the inner tissue of the marine red alga Liagora viscida the fungus Drechslera dematioidea was isolated. After mass cultivation, the fungus was investigated for its secondary metabolite content, and 10 new sesquiterpenoids [isosativenetriol (1), drechslerines A (2) and B (3), 9-hydroxyhelminthosporol (5), drechslerines C-G (6-10), and sativene epoxide (12)] were isolated. Compounds 8 and 10 exhibited antiplasmodial activity against Plasmodium falciparum strains K1 and NF54. The known compounds helminthosporol (4), cis-sativenediol (11), isocochlioquinone A (14), isocochlioquinone C (15), and cochlioquinone B (16) were also isolated. All structures were elucidated using spectroscopic methods, mainly 1D and 2D NMR and MS.

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Citations

Jan 24, 2006·Journal of Industrial Microbiology & Biotechnology·Punyasloke BhaduryPhillip C Wright
May 24, 2012·Chemical Reviews·Kye-Simeon Masters, Stefan Bräse
Oct 20, 2007·Journal of Natural Products·Huarong HuangWenhan Lin
Jul 15, 2011·Journal of Asian Natural Products Research·Gao-Fei ZhangHui-Ming Ge
Dec 17, 2008·PLoS Neglected Tropical Diseases·Fernanda Fraga CamposCarlos Leomar Zani
Mar 1, 2012·Marine Drugs·Feng-Ping MiaoNai-Yun Ji
Oct 16, 2010·Marine Drugs·Rainer Ebel
Jan 1, 2015·Applied Microbiology and Biotechnology·Ravindra Pal SinghC R K Reddy
Apr 6, 2017·Chemical Reviews·Franck Le BideauFrançoise Dumas
Oct 26, 2005·Chembiochem : a European Journal of Chemical Biology·Gabriele M KönigDaniela Müller
Dec 25, 2012·Natural Product Reports·John W BluntMichèle R Prinsep
Mar 12, 2020·Natural Product Research·Giada d'ErricoFrancesco Vinale
Oct 27, 2015·Journal of Asian Natural Products Research·Hong-Lian AiHua-Chun Guo
Sep 11, 2019·Beilstein Journal of Organic Chemistry·Chin-Soon PhanYit-Heng Chooi
Aug 28, 2020·Journal of Agricultural and Food Chemistry·Yuan-Yuan LiGang Ding
Nov 26, 2002·The Journal of Organic Chemistry·Martin EipertMartin E Maier
May 24, 2003·Journal of Natural Products·Ahmed Abdel-LateffAnthony D Wright

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