Rare Signet Ring Cell Adenocarcinoma of the Colon Metastasis to the Orbit

Case Reports in Ophthalmological Medicine
Colin Bacorn, Lily Koo Lin

Abstract

Metastases arising from primary tumors of the gastrointestinal tract are not commonly encountered in the orbit. Colorectal carcinomas are subcategorized based on morphological and genetic characteristics with these distinctions bearing therapeutic and prognostic significance. The behavior of these subcategories, including their propensity for orbital metastasis, differs, and clinicians treating these tumors must be aware of their metastatic profiles. This report describes a 51-year-old female with right upper lid swelling and ptosis ultimately found, what we believe to be, the first reported case of signet ring cell colon carcinoma metastasizing to the levator muscle and superior orbit. This case serves as a reminder to all clinicians to consider orbital metastasis even in malignancies not typically found in this location.

References

Oct 1, 1974·Archives of Ophthalmology·A P Ferry, R L Font
Jul 1, 1996·Annals of Surgical Oncology·T AnthonyN J Petrelli
Oct 20, 2001·Ophthalmic Plastic and Reconstructive Surgery·J A ShieldsR C Eagle
Apr 29, 2006·Asian Journal of Surgery·Raja B HishamYunus A Gul
Jul 27, 2006·The Australasian Journal of Dermatology·Roberto Cecchi, Valentina Rapicano
Nov 23, 2006·Ophthalmic Plastic and Reconstructive Surgery·Jacob J YunkerJohn A Long
Feb 22, 2008·International Journal of Dermatology·Line BreitingJeanette Falck Winther
Feb 2, 2011·Orbit·Bryan K MonsonChang Hee Kim
Feb 18, 2011·Ophthalmic Plastic and Reconstructive Surgery·Norman C CharlesChristopher I Zoumalan
Apr 27, 2013·Journal français d'ophtalmologie·T ChekrineA Benider
Sep 23, 2014·BMJ Case Reports·Ethan B LudmirManisha Palta
Mar 19, 2015·Hematology/oncology and Stem Cell Therapy·Muhammad Rizwan KhawajaE Gabriela Chiorean
Nov 26, 2015·Case Reports in Oncology·Peter Y ParkMadappa N Kundranda
Mar 15, 2016·Ophthalmic Plastic and Reconstructive Surgery·Meredith S BakerErin M Shriver
Apr 25, 2017·Cancer Epidemiology·Jamaica R RobinsonAmanda I Phipps
Aug 5, 2017·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Weijie V LinAndrew G Lee
Aug 9, 2017·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Sebastian StintzingHeinz-Josef Lenz
Sep 20, 2017·Surgical Oncology Clinics of North America·Naruhiko IkomaGeorge Chang
Dec 28, 2017·Critical Reviews in Oncology/hematology·Nele BoeckxKen Op de Beeck
Jan 9, 2019·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
May 2, 2019·BMJ Case Reports·Mariana Morales-CruzJorge Humberto Rodríguez-Quintero

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ophthalmic Plastic and Reconstructive Surgery
Norman C CharlesChristopher I Zoumalan
Revista médica de Chile
S San MartínJ Arraztoa
Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie
Anales de medicina interna : organo oficial de la Sociedad Española de Medicina Interna
M J MoroL Requena
© 2021 Meta ULC. All rights reserved