Tritiated corticosterone injected subcutaneously into adrenalectomized male rats 1 hour before killing produced intense labeling of the hippocampus in radioautograms prepared by a method that reduced or prevented diffusion of the radioactive material. The pyramidal neurons of the cornu ammonis and the granule neurons of the gyrus dentatus contained more radioactivity than did other regions of the brain; however, the intensity of labeling varied among adjacent neurons. The nuclei of many neurons were clearly labeled but radioactivity was relatively sparse in the cytoplasm, in the axons where they branch from cell bodies, and in adjacent neuropil.
Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration
Adrenal steroids and plasticity of hippocampal neurons: toward an understanding of underlying cellular and molecular mechanisms
Different regulation of serotonin receptors following adrenal hormone imbalance in the rat hippocampus and hypothalamus
Glucocorticoids and the hippocampus. Developmental interactions facilitating the expression of behavioral inhibition
RAAS escape: a real clinical entity that may be important in the progression of cardiovascular and renal disease
Autoradiographic localization of [3H]estradiol related to steroid responsiveness in cultures of the newborn mouse hypothalamus and preoptic area
Hippocampal corticosterone receptors and novelty-induced behavioral activity: effect of kainic acid lesion in the hippocampus
Glucocorticoids modulate the response of ornithine decarboxylase to unilateral removal of the dorsal hippocampus
Stress-induced activation of the hippocampal cholinergic system and the pituitary-adrenocortical axis
Corticosterone modulation of neurotransmitter receptors in rat hippocampus: a quantitative autoradiographic study
Corticosterone and dexamethasone act at different brain sites to inhibit adrenalectomy-induced adrenocorticotropin hypersecretion
Time-dependent effects of posttraining intrahippocampal injections of corticosterone on retention of appetitive learning tasks in mice
Characterization of the effects of the acute and repeated administration of MK-801 on the release of adrenocorticotropin, corticosterone and prolactin in the rat
Sprouting responsiveness in the dentate gyrus is reduced by ethanol administered following but not preceding an entorhinal lesion
Anatomical resolution of two types of corticosterone receptor sites in rat brain with in vitro autoradiography and computerized image analysis
In vivo competitive autoradiographic study of [3H]corticosterone and [3H]aldosterone binding sites within mouse brain hippocampus
Investigation of the corticosteroid receptor system in rat hippocampus by ion exchange fast protein liquid chromatography
The effects of postoperative time intervals and diurnal variation on liver glycogen levels in rats with hippocampal lesions
Adrenal steroids and extinction behavior: antagonism by progesterone, deoxycorticosterone and dexamethasone of a specific effect of corticosterone
Corticosterone decreases the efficacy of adrenaline to affect passive avoidance retention of adrenalectomized rats
Adrenalectomy fails to alter radial maze performance of rats at retention intervals of 24 hours or less
Maturation of the adrenocortical stress response: neuroendocrine control mechanisms and the stress hyporesponsive period
Perinatal development of estrogen receptors in mouse brain assessed by radioautography, nuclear isolation and receptor assay
Prenatal ethanol exposure alters the post-lesion reorganization (sprouting) of acetylcholinesterase staining in the dentate gyrus of adult rats
The role of serotonin in the development and environmental regulation of type II corticosteroid receptor binding in rat hippocampus
A neurogenetic and morphogenetic approach to hippocampal functions based on individual differences and neurobehavioral covariations
Mineralocorticoid and glucocorticoid receptors in the brain. Implications for ion permeability and transmitter systems
A comparison of the distribution of acetylcholinesterase and muscarinic cholinergic receptors in the feline neostriatum
Autoradiographic localization of glucocorticosteroid binding sites in rat brain after in vivo injection of [3H]RU 28362
Labelling of Schwann and satellite cells by [3H]dexamethasone in a rat sympathetic ganglion and sciatic nerve
Opposing roles of type I and type II adrenal steroid receptors in hippocampal long-term potentiation
Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: involvement of glucocorticoid secretion and excitatory amino acid receptors
The stress-induced response of the septo-hippocampal cholinergic system. A vectorial outcome of psychoneuroendocrinological interactions
Feedback action and tonic influence of corticosteroids on brain function: a concept arising from the heterogeneity of brain receptor systems
Influence of cadmium chloride, mercuric chloride, and sodium vanadate on the glutathione-conjugating enzyme system in liver, kidney, and brain of mice
Breast cancer affects both the hippocampus volume and the episodic autobiographical memory retrieval
Autoradiographic localization of hormone-concentrating cells in the brain of the female rhesus monkey
Chronic stress and brain plasticity: Mechanisms underlying adaptive and maladaptive changes and implications for stress-related CNS disorders
Adrenocorticoid receptor binding in the rat hippocampus: strain-dependent covariations with arousal and habituation to novelty
The permissive effect of cortical steroids on the induction of brain ornithine decarboxylase by nerve growth factor
Antagonistic effects of aldosterone on corticosterone-mediated changes in exploratory behavior of adrenalectomized rats
Axonal transport in the efferent pathways of the hippocampus: labeling of projection areas after (3H)valine injections
Interactions in vivo and in vitro of corticoids and progesterone with cell nuclei and soluble macromolecules from rat brain regions and pituitary
Altered regulation of lesion-induced synaptogenesis by adrenalectomy and corticosterone in young adult rats
Effects of the antiglucocorticoid RU 38486 on the induction of learned helpless behavior in Sprague-Dawley rats
Opposite effects on NCAM expression in the rat frontal cortex induced by acute vs. chronic corticosterone treatments
Adrenocortical steroids modify neurotransmitter-stimulated cyclic AMP accumulation in the hippocampus and limbic brain of the rat
Evidence for glucocorticoid target cells in the rat optic nerve. Hormone binding and glycerolphosphate dehydrogenase induction
Central glucocorticoid receptor immunoreactive neurons: new insights into the endocrine regulation of the brain
Evidence for and against the Naples high- and low-excitability rats as genetic model to study hippocampal functions
Corticosterone binding to hippocampus: immediate and delayed influences of the absence of adrenal secretion
Corticosteroid receptor plasticity and recovery of a deficient hippocampus-associated behavior after unilateral (dorsal) hippocampectomy
Cells in regions of rhesus monkey brain and pituitary retain radioactive estradiol, corticosterone and cortisol differentially
Role of fetoneonatal estrogen binding proteins in the associations of estrogen with neonatal brain cell nuclear receptors
Effect of steroid competition and time on the uptake of (3H)corticosterone in the rat brain; an autoradiographic study
Decreased serotonin turnover in the dorsal hippocampus of rat brain shortly after adrenalectomy: selective normalization after corticosterone substitution
Actions and interactions of estradiol and glucocorticoids in cognition and the brain: Implications for aging women
60 YEARS OF NEUROENDOCRINOLOGY: Redefining neuroendocrinology: stress, sex and cognitive and emotional regulation
Prenatal gonadal steroids affect adult spatial behavior, CA1 and CA3 pyramidal cell morphology in rats
The brain Renin-angiotensin system controls divergent efferent mechanisms to regulate fluid and energy balance
Steroid suppression of axon sprouting in the hippocampal dentate gyrus of the adult rat: dose-response relationship
Study of molecular and granular layer of dentate gyrus of female rats neonatally treated with estrogen
Modulation of stress consequences by hippocampal monoaminergic, glutamatergic and nitrergic neurotransmitter systems
Light autoradiographic localisation of cholinergic muscarinic receptors in rat brain by specific binding of a potent antagonist
30 YEARS OF THE MINERALOCORTICOID RECEPTOR: The brain mineralocorticoid receptor: a saga in three episodes
Effect of chronic administration of selective glucocorticoid receptor antagonists on the rat hypothalamic-pituitary-adrenocortical axis
Hyperthermia-induced seizures followed by repetitive stress are associated with age-dependent changes in specific aspects of the mouse stress system
Multidrug resistance P-glycoprotein hampers the access of cortisol but not of corticosterone to mouse and human brain
Hypothalamic-pituitary-adrenocortical axis changes in a transgenic mouse with impaired glucocorticoid receptor function
Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice
Dexamethasone and corticosterone receptor sites. Differential topographic distribution in rat hippocampus revealed by high resolution autoradiography
Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model.
Neuroendocrine, neuroinflammatory and pathological outcomes of chronic stress: A story of microglial remodeling.
Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.
Evolution of Pluripotency
Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.
Lipidomics & Rhinovirus Infection
Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.
Alzheimer's Disease: MS4A
Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.
Chronic Fatigue Syndrome
Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.
Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.
Generating Insulin-Secreting Cells
Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.
Central Pontine Myelinolysis
Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.
Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.