Rat hepatitis E virus: geographical clustering within Germany and serological detection in wild Norway rats (Rattus norvegicus)

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases
Reimar JohneRainer G Ulrich

Abstract

Zoonotic hepatitis E virus (HEV) infection in industrialised countries is thought to be caused by transmission from wild boar, domestic pig and deer as reservoir hosts. The detection of HEV-specific antibodies in rats and other rodents has suggested that these animals may represent an additional source for HEV transmission to human. Recently, a novel HEV (ratHEV) was detected in Norway rats from Hamburg, Germany, showing the typical genome organisation but a high nucleotide and amino acid sequence divergence to other mammalian and to avian HEV strains. Here we describe the multiple detection of ratHEV RNA and HEV-specific antibodies in Norway rats from additional cities in north-east and south-west Germany. The complete genome analysis of two novel strains from Berlin and Stuttgart confirmed the association of ratHEV to Norway rats. The present data indicated a continuing existence of this virus in the rat populations from Berlin and Hamburg. The phylogenetic analysis of a short segment of the open reading frame 1 confirmed a geographical clustering of the corresponding sequences. Serological investigations using recombinant ratHEV and genotype 3 capsid protein derivatives demonstrated antigenic differences which might be cause...Continue Reading

References

Mar 1, 1988·The Journal of General Virology·D BradleyM Kane
Feb 11, 2000·The Journal of Infectious Diseases·M O FavorovH S Margolis
May 31, 2001·Journal of Viral Hepatitis·V A ArankalleV S Padbidri
Aug 29, 2001·Bioinformatics·J P Huelsenbeck, F Ronquist
Jul 13, 2002·Journal of Medical Virology·You-Chun WangTim J Harrison
Aug 9, 2003·Lancet·Shuchin TeiShunji Mishiro
Aug 13, 2003·Bioinformatics·Fredrik Ronquist, John P Huelsenbeck
Jul 16, 2005·Memórias do Instituto Oswaldo Cruz·Cláudia L VitralAna Maria C Gaspar
Feb 21, 2006·Emerging Infectious Diseases·Tian-Cheng LiTatsuo Miyamura
Oct 21, 2006·Journal of Viral Hepatitis·V A ArankalleM S Chadha
Apr 10, 2008·Molecular Biology and Evolution·David Posada
Feb 6, 2009·The Journal of Veterinary Medical Science·Chieko SakanoHirokazu Kimura
Apr 14, 2009·Veterinary Microbiology·X J Meng
Jun 25, 2009·Journal of Medical Virology·Chenyan ZhaoYouchun Wang
Nov 6, 2009·The Journal of General Virology·Reimar JohneAnika Schielke
Aug 5, 2010·Current Opinion in Infectious Diseases·Nicole Pavio, Jean-Michel Mansuy
Aug 26, 2010·Emerging Infectious Diseases·Reimar JohneRainer G Ulrich
Jan 15, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Yansheng GengYouchun Wang
Feb 25, 2011·Virus Research·Imran AhmadShahid Jameel
Apr 5, 2011·Virus Research·Rakesh Aggarwal
Dec 17, 2011·Emerging Infectious Diseases·Robert H PurcellSuzanne U Emerson

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Citations

Apr 30, 2013·Veterinary Microbiology·Wei LiChang Wen Ke
Jan 25, 2013·Intervirology·Mamadou KabaPhilippe Colson
Dec 25, 2012·Emerging Infectious Diseases·Tian-Cheng LiWakita Takaji
Jul 24, 2013·Emerging Infectious Diseases·Dawei GuanChangwen Ke
May 2, 2014·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·J JacobE Schmolz
Apr 20, 2014·Medical Microbiology and Immunology·Andi KrumbholzRoland Zell
Mar 22, 2013·The Journal of General Virology·Suzanne U EmersonAndrew E Firth
Dec 4, 2013·The Journal of General Virology·Jay LinFrederik Widén
Apr 29, 2015·Transboundary and Emerging Diseases·D ThiryE F de Oliveira-Filho
Jul 23, 2014·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Reimar JohneRainer G Ulrich
Jan 30, 2015·Vector Borne and Zoonotic Diseases·Michael KosoySerge Morand
Jun 15, 2016·Pest Management Science·Elisa HeuserRainer G Ulrich
Jan 11, 2017·BioMed Research International·Pilar Clemente-CasaresAntonio Mas
Feb 7, 2018·Archives of Virology·Putu Prathiwi PrimadharsiniHiroaki Okamoto
Dec 3, 2017·The Veterinary Record·Sylvia GriersonRichard P Smith
Jun 21, 2017·EcoHealth·Jamie L RothenburgerClaire M Jardine
Sep 26, 2017·Zoonoses and Public Health·C SpahrR Johne
Apr 4, 2018·Cold Spring Harbor Perspectives in Medicine·Anna-Lena SanderJan Felix Drexler
Jan 10, 2019·Pest Management Science·Anna ObiegalaMartin Pfeffer
Aug 11, 2017·Proceedings. Biological Sciences·Moritz SaxenhoferGerald Heckel
May 4, 2017·Journal of Medical Virology·Feiyan LongFen Huang
Oct 9, 2019·Zoonoses and Public Health·Luca De SabatoIlaria Di Bartolo
Oct 21, 2016·European Journal of Gastroenterology & Hepatology·Marten SchulzEckart Schott
Feb 13, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Mara Lucia GravinattiFábio Gregori
Nov 1, 2016·The Journal of Veterinary Medical Science·Satomu ObanaJiro Arikawa
May 22, 2019·Viruses·Putu Prathiwi PrimadharsiniHiroaki Okamoto
May 22, 2019·Viruses·Scott P Kenney
May 28, 2021·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Péter PankovicsGábor Reuter
Jun 16, 2021·Applied Microbiology and Biotechnology·Barbara KubickovaRainer G Ulrich

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