PMID: 11335005May 4, 2001Paper

Rat retinal progenitor cells and a retinal pigment epithelial factor

Brain Research. Developmental Brain Research
H J SheedloR S Roque

Abstract

Retinal progenitor cells were isolated from explants of neonatal rat retinas and characterized by transmission electron microscopy and reverse transcriptase-polymerase chain reaction and by their response to an isolated retinal pigment epithelial cell cell factor. The isolated progenitor cells demonstrated nuclei with abundant euchromatin typical of progenitor cells and showed the presence of nestin and opsin message. A protein ( approximately 67 kDa) isolated from conditioned media of cultured rat RPE cells promoted the survival of isolated retinal progenitor cells.

References

Aug 1, 1989·Experimental Eye Research·P A CampochiaroL M Hjelmeland
Jan 1, 1995·Annual Review of Neuroscience·F H GageL J Fisher
May 1, 1995·In Vitro Cellular & Developmental Biology. Animal·H J SheedloJ E Turner
Dec 5, 1995·Proceedings of the National Academy of Sciences of the United States of America·F H GageJ Ray
May 31, 1996·Brain Research. Developmental Brain Research·H J Sheedlo, J E Turner
May 29, 1998·Brain Research. Developmental Brain Research·H J SheedloJ E Turner

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