Rate control in patients with atrial fibrillation

Annales de cardiologie et d'angéiologie
F Anselme

Abstract

The objectives of rate control in patients with atrial fibrillation is to reduce symptoms, improve quality of live and minimize the risk of heart failure development. Based upon results of large randomized studies, this strategy can be chosen as a first line therapy in some patients including those with heart failure. The target ventricular rate is <or=85 bpm at rest and <or=115 bpm during moderate exercise. Drugs slowing the atrioventricular conduction are usually used alone or in combination to achieve this goal. Failure to control ventricular rate using drugs may lead to AV nodal ablation and pacemaker implantation with a conventional or a biventricular system according to patient initial hemodynamic conditions.

References

Dec 6, 2002·The New England Journal of Medicine·D G WyseUNKNOWN Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Investigators
Dec 6, 2002·The New England Journal of Medicine·Isabelle C Van GelderUNKNOWN Rate Control versus Electrical Cardioversion for Persistent Atrial Fibrillation Study Group
Dec 10, 2003·Journal of the American College of Cardiology·Aleem U KhandJohn G F Cleland
Nov 24, 2005·Journal of Cardiovascular Electrophysiology·Rahul N DoshiUNKNOWN PAVE Study Group
Jun 21, 2008·The New England Journal of Medicine·Denis RoyUNKNOWN Atrial Fibrillation and Congestive Heart Failure Investigators

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